Observation on efficacy of combined traditional Chinese and western medicine treatment of renal anemia with roxadustat and Shengxuening in the treatment of renal anemia
Objective To observe the effect of combined traditional Chinese and western medicine treatment of renal anemia with roxadustat and Shengxuening. Methods 90 patients with renal anemia were divided into group A,group B and group C according to random numerical table,with 30 people in each group. Group A was treated with oral roxadustat and Shengxuening,group B was treated with oral roxadustat and ferrous succinate sustained release tablets,and group C was only treated with oral roxadustat. The levels of hemoglobin (Hb),hematocrit (Hct),serum ferritin (SF) and traditional Chinese medicine syndrome score before and after treatment,and the occurrence of adverse reactions were compared among the three groups. Results After treatment,Hb,Hct and SF in the three groups were higher than those before treatment;group A had Hb of (112.83±14.77) g/L,Hct of (37.10±10.98)％ and SF of (267.11±54.65) μg/L,which were higher than (99.62±17.78) g/L,(30.61±5.44)％ and (219.81±63.70) μg/L in group B,and (102.76±15.38) g/L,(31.86±4.64)％ and (209.82±60.93) μg/L in group C;there were statistical significance (P<0.05). There was no significant difference in Hb,Hct and SF between group B and group C (P>0.05). After treatment,the scores of tiredness and fatigue,pale complexion and loss of appetite in the three groups were lower than those before treatment;in group A,the score of tiredness and fatigue was (1.33±0.60) points,the score of pale complexion was (1.36±0.49) points and the score of loss of appetite was (1.13±0.34) points,which were lower than (1.73±0.62),(1.70±0.74) and (1.50±0.73) points in group B,and (1.80±0.76),(1.76±0.62) and (1.50±0.57) points in group C;there were statistical significance (P<0.05). Comparison of the scores of tiredness and fatigue,pale complexion and loss of appetite in group B and group C,the difference was not statistically significant (P>0.05). The incidence rate of adverse reactions in group B was 6.7％,and there were no adverse reactions in group A and group C. Comparison of the incidence of adverse reactions among the three groups showed no statistical difference (P>0.05). Conclusion The combination of traditional Chinese and Western medicine with rosacetam and Shengxuening in the treatment of renal anemia is more effective than the combination of ferrous succinate or roxadustat alone,and there are no adverse reactions.
Renal anemiaChronic kidney diseaseRoxadustat capsuleShengxuening tabletsFerrous succinate sustained release tabletsCombined traditional Chinese and western medicine
万方数据
维普
