Observation on the curative effect of Xiaoyao Pill combined with modified Siwu Decoction in the treatment of menstrual disorders
Objective To explore the clinical effect of Xiaoyao Pill combined with modified Siwu Decoction in the treatment of patients with menstrual disorders. Methods 70 patients with menstrual disorders were selected and divided into a control group (n=35,conventional Western medicine treatment) and a study group (n=35,conventional Western medicine treatment on the basis of Xiaoyao Pill and modified Siwu Decoction) according to random numerical table. Comparison was made on therapeutic effect,serum sex hormone[follicle stimulating hormone (FSH),luteinizing hormone (LH),estradiol (E2)]levels,traditional Chinese medicine syndrome score,hemorheology,incidence of adverse reactions and recurrence rate between the two groups. Results The total effective rate of 94.29％ in the study group was higher than 74.29％ in the control group (P<0.05). After treatment,FSH and LH levels in the study group were lower than those in the control group,and E2 level was higher than that in the control group (P<0.05). After treatment,the study group had menstrual cycle score of (0.82±0.23) points,menstrual volume score of (0.92±0.32) points,menstrual period score of (1.05±0.36) points,menstrual color score of (0.75±0.26) points,and menstrual quality score of (0.82±0.33) points,which were lower than (1.52±0.32),(1.42±0.42),(1.35±0.28),(1.48±0.32),and (1.28±0.23) points in the control group (P<0.05). After treatment,the study group had whole-blood high-shear viscosity of (4.15±0.42) mPa·s,whole-blood low-shear viscosity of (7.62±0.61) mPa·s,and plasma viscosity of (1.31±0.22) mPa·s,which were lower than (5.32±0.38),(9.52±0.72),and (1.56±0.42) mPa·s in the control group (P<0.05). The incidence of adverse reactions of 5.71％ in the study group was lower than 25.72％ in the control group (P<0.05). The recurrence rate of 2.86％ in the study group was lower than 22.86％ in the control group (P<0.05). Conclusion In patients with menstrual disorders,Xiaoyao Pill combined with modified Siwu Decoction can improve the serum sex hormone level and hemorheology,alleviate the clinical symptoms,and the incidence of adverse effects and recurrence rate are low,so the therapeutic effect is definite.
Menstrual disordersXiaoyao PillSiwu DecoctionTraditional Chinese medicine syndrome scoreSex hormonesHemorheology
万方数据
维普
