Analysis of the effect of medical nutrition therapy combined with exercise therapy on delivery outcome of pregnant women with gestational diabetes mellitus
Objective To observe the improvement effect of medical nutrition therapy (MNT) combined with exercise therapy on delivery outcome of pregnant women with gestational diabetes mellitus (GDM). Methods According to different intervention methods,200 pregnant women diagnosed with GDM were divided into a study group (medical nutrition therapy combined with exercise therapy intervention) and a control group (conventional diet and exercise guidance intervention),each with 100 cases. The results of oral glucose tolerance test (OGTT) and lipid parameters before intervention and at 42 d after delivery,delivery status and adverse neonatal outcomes were compared between the two groups. Results Before intervention,there was no significant difference in results of oral glucose tolerance test,total cholesterol (TC) and triglyceride (TG) between the two groups (P>0.05). At 42 d after delivery,the results of oral glucose tolerance test,TC and TG in both groups decreased compared with those before intervention;in the study group,the fasting blood glucose was (4.59±0.52) mmol/L,1-h blood glucose was (9.17±0.61) mmol/L,2-h blood glucose was (7.12±0.69) mmol/L,TC was (2.92±0.17) mmol/L and TG was (1.21±0.34) mmol/L,which were lower than (6.06±1.03),(10.87±0.85),(8.05±0.74),(4.34±0.18),and (2.05±0.35) mmol/L in the control group,and the difference was statistically significant (P<0.05). The incidence rates of premature rupture of membranes,premature delivery,postpartum hemorrhage,fetal distress and fetal macrosomia were 5.00%,2.00%,1.00%,7.00% and 2.00% in the study group,which were lower than 14.00%,9.00%,8.00%,16.00% and 11.00% in the control group,and the difference was statistically significant (P<0.05). The incidence of cesarean section in the study group was slightly lower than that in the control group,but there was no significant difference between the two groups (P>0.05). The incidence rates of neonatal hypoglycemia,pneumonia and hyperbilirubinemia were 2.00%,2.00% and 7.00% in the study group,which were lower than 11.00%,9.00% and 16.00% in the control group,and the difference between the two groups was statistically significant (P<0.05). Conclusion Medical nutritional therapy combined with exercise therapy shows satisfactory effect in pregnant women with GDM,which can control the results of oral glucose tolerance test and lipid levels at 42 d after delivery,and improve delivery situation of pregnant women and the adverse outcome of neonates.