首页|医学营养治疗联合运动疗法干预对妊娠期糖尿病产妇分娩结局的影响分析

医学营养治疗联合运动疗法干预对妊娠期糖尿病产妇分娩结局的影响分析

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目的 观察医学营养治疗(MNT)联合运动疗法干预对妊娠期糖尿病(GDM)产妇分娩结局的影响。方法 200例确诊为GDM的产妇作为研究对象,根据产妇接受的干预方法不同分成研究组(予以医学营养治疗联合运动疗法干预)、对照组(予以常规饮食及运动指导干预),各100例。对比两组干预前、产后42 d时的口服葡萄糖耐量(OGTT)试验结果与血脂指标,分娩情况,新生儿不良结局发生情况。结果 干预前,两组口服葡萄糖耐量试验结果与总胆固醇(TC)、甘油三酯(TG)相比,无显著差异性(P>0。05)。产后42 d时,两组产妇的口服葡萄糖耐量试验结果与TC、TG均较干预前下降,且研究组产妇的口服葡萄糖耐量试验空腹血糖(4。59±0。52)mmol/L、1 h血糖(9。17±0。61)mmol/L、2 h血糖(7。12±0。69)mmol/L与TC(2。92±0。17)mmol/L、TG(1。21±0。34)mmol/L均低于对照组的(6。06±1。03)、(10。87±0。85)、(8。05±0。74)、(4。34±0。18)、(2。05±0。35)mmol/L,差异具有统计学意义(P<0。05)。研究组胎膜早破、早产、产后出血、胎儿宫内窘迫及巨大儿的发生率分别为5。00%、2。00%、1。00%、7。00%、2。00%,均低于对照组的14。00%、9。00%、8。00%、16。00%、11。00%,差异具有统计学意义(P<0。05)。而两组剖宫产发生率相比,研究组稍低于对照组,但相比无显著差异性(P>0。05)。研究组新生儿低血糖、肺炎、高胆红素血症的发生率分别为2。00%、2。00%、7。00%,均低于对照组的11。00%、9。00%、16。00%,差异具有统计学意义(P<0。05)。结论 GDM产妇以医学营养治疗联合运动疗法进行干预,可控制产妇产后42 d口服葡萄糖耐量试验结果及血脂指标水平,改善产妇分娩情况与新生儿不良结局,效果理想。
Analysis of the effect of medical nutrition therapy combined with exercise therapy on delivery outcome of pregnant women with gestational diabetes mellitus
Objective To observe the improvement effect of medical nutrition therapy (MNT) combined with exercise therapy on delivery outcome of pregnant women with gestational diabetes mellitus (GDM). Methods According to different intervention methods,200 pregnant women diagnosed with GDM were divided into a study group (medical nutrition therapy combined with exercise therapy intervention) and a control group (conventional diet and exercise guidance intervention),each with 100 cases. The results of oral glucose tolerance test (OGTT) and lipid parameters before intervention and at 42 d after delivery,delivery status and adverse neonatal outcomes were compared between the two groups. Results Before intervention,there was no significant difference in results of oral glucose tolerance test,total cholesterol (TC) and triglyceride (TG) between the two groups (P>0.05). At 42 d after delivery,the results of oral glucose tolerance test,TC and TG in both groups decreased compared with those before intervention;in the study group,the fasting blood glucose was (4.59±0.52) mmol/L,1-h blood glucose was (9.17±0.61) mmol/L,2-h blood glucose was (7.12±0.69) mmol/L,TC was (2.92±0.17) mmol/L and TG was (1.21±0.34) mmol/L,which were lower than (6.06±1.03),(10.87±0.85),(8.05±0.74),(4.34±0.18),and (2.05±0.35) mmol/L in the control group,and the difference was statistically significant (P<0.05). The incidence rates of premature rupture of membranes,premature delivery,postpartum hemorrhage,fetal distress and fetal macrosomia were 5.00%,2.00%,1.00%,7.00% and 2.00% in the study group,which were lower than 14.00%,9.00%,8.00%,16.00% and 11.00% in the control group,and the difference was statistically significant (P<0.05). The incidence of cesarean section in the study group was slightly lower than that in the control group,but there was no significant difference between the two groups (P>0.05). The incidence rates of neonatal hypoglycemia,pneumonia and hyperbilirubinemia were 2.00%,2.00% and 7.00% in the study group,which were lower than 11.00%,9.00% and 16.00% in the control group,and the difference between the two groups was statistically significant (P<0.05). Conclusion Medical nutritional therapy combined with exercise therapy shows satisfactory effect in pregnant women with GDM,which can control the results of oral glucose tolerance test and lipid levels at 42 d after delivery,and improve delivery situation of pregnant women and the adverse outcome of neonates.

Medical nutrition therapyExercise therapyGestational diabetes mellitusOral glucose tolerance testAdverse neonatal outcomes

陈娟娟、范岩峰、林斯华

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361003 厦门大学附属妇女儿童医院/厦门市妇幼保健院

医学营养治疗 运动疗法干预 妊娠期糖尿病 口服葡萄糖耐量试验 新生儿不良结局

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(20)