A study on the clinical effect of small bone window craniotomy in the treatment of hypertensive intercerebral hemorrhage
Objective To explore the effect of small bone window craniotomy in the treatment of hypertensive intercerebral hemorrhage (HICH).Methods 70 patients with HICH were selected and divided into a control group and a study group by computer random number table method,with 35 cases in each group.The control group was given conventional treatment,and the study group was given small bone window craniotomy.Patients in both groups were compared in terms of National Institutes of Health Stroke Scale (NIHSS) score,surgical indicators (operation time,intraoperative blood loss,consciousness recovery time,and hospitalization time),related indicators[serum S100B protein,neuron-specific enolase (NSE),brain-derived neurotrophic factor (BDNF)],therapeutic effect,and complications.Results After 15 and 30 d of treatment,NIHSS scores of the study group were (11.83±2.62) and (6.42±1.11) points,which were lower than (16.87±1.86) and (10.68±1.09) points of the control group,and the difference was statistically significant (P<0.05).In the study group,the operation time was (1.52±0.42) h,the consciousness recovery time was (1.65±0.52) d,and the hospitalization time was (15.52±3.22) d,which were shorter than (2.45±0.38) h,(4.52±0.39) d,and (25.86±2.68) d in the control group;the intraoperative blood loss of (72.54±5.42) ml in the study group was lower than (157.52±5.86) ml in the control group;the difference was statistically significant (P<0.05).After treatment,the study group had S100B protein of (0.54±0.12) μg/L and NSE of (10.25±2.14) ng/ml,which were lower than (0.87±±0.17) μg/L and (15.86±2.21) ng/ml in the control group;BDNF of (7.17±1.05) μg/L in the study group was higher than (5.48±0.68) μg/L in the control group;the difference was statistically significant (P<0.05).The total effective rate of the study group (94.29％) was higher than that of the control group (74.29％),and the difference was statistically significant (x2=5.2851,P<0.05).The complication rate of the study group (5.71％) was lower than that of the control group (31.43％),and the difference was statistically significant (x2=7.6518,P<0.05).Conclusion The effect of small bone window craniotomy in the treatment of HICH patients is significant,which can reduce the risk of complications,reduce neurological damage,improve the serum level of patients,and is worthy of clinical promotion.
Hypertensive intracerebral hemorrhageSmall bone window craniotomyNeurological deficitTherapeutic effect
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