Analysis of one and multiple risk factors of carotid plaque echo
Objective To explore the one and multiple risk factors of carotid plaque echo.Methods A total of 167 hospitalized patients who underwent head magnetic resonance imaging,two-dimensional carotid ultrasound and color Doppler ultrasound were retrospectively collected.According to the results of two-dimensional carotid ultrasound and color Doppler ultrasound,the patients were divided into no plaque group (n=35),one type of echoplaque group (n=101),two types of echoplaque group (n=22),and three types of echoplaque group (n=9).Univariate analysis was used to compare the general information and comorbidities of the four groups.Logistic regression models were constructed to analyze the one and multiple risk factors of carotid plaque echo using the factors with statistically significant differences in the univariate analysis.Results Comparison of gender,body mass index (BMI),percentages of smoking,alcohol consumption,diabetes mellitus and hyperlipidemia among the four groups showed no statistically significant difference (P>0.05).The age,percentage of coronary heart disease,percentage of hypertension,and percentage of cerebral small-vessel disease in the no plaque group were (56.1±8.9) years old,31.4％ (11/35),28.6％ (10/35),and 42.9％ (15/35),those in the one type of echoplaque group were (62.1±7.8) years old,53.5％ (54/101),37.6％ (38/101),73.3％ (74/101),those in two types of echoplaque group were (61.8±8.4) years old,68.2％ (15/22),50.0％ (11/22),and 95.5％ (21/22),and those in three types of echoplaque group were (70.2±5.2) years old,66.7％ (6/9),77.8％ (7/9),and 88.9％ (8/9).Comparison of age,percentages of coronary heart disease,hypertension and cerebral small-vessel disease in the four groups showed statistically significant differences (P<0.05).Multivariate Logistic regression analysis showed that advanced age and cerebral small-vessel disease were the risk factors for the development of one type of echoplaque (P<0.05);and the risk of developing one type of echoplaque in patients ≥60 years of age was 2.983 times higher than those<60 years of age,and the risk of developing one type of echoplaque in patients with cerebral small-vessel disease was 3.475 times higher than those without cerebral small-vessel disease.Cerebral small-vessel disease was a risk factor for the development of two types of echoplaque (P<0.05);and the risk of developing two types of echoplaque in patients with cerebral small-vessel disease was 23.875 times that of patients without cerebral small-vessel disease.Advanced age was a risk factor for developing three types of echoplaque (P<0.05);and the risk for the development three types of echoplaque in patients ≥60 years of age was 9.836 times higher than those<60 years of age.Conclusion Advanced age and cerebral small-vessel disease are independent risk factors for echoplaque.Cerebral small-vessel disease is an independent risk factor for the two types of echoplaque,and advanced age is an independent risk factor for the three types of echoplaque.
万方数据
维普
