The effect of intravascular thrombectomy combined with alteplase intravenous thrombolysis in the treatment of acute cerebral infarction in the elderly and its impact on patients' neurological function
Objective To explore the effect of intravascular thrombectomy combined with alteplase intravenous thrombolysis in the treatment of acute cerebral infarction (ACI) in the elderly and its impact on patients' neurological function.Methods A retrospective analysis was conducted on the clinical data of 80 elderly ACI patients,who were divided into a control group (intravenous thrombolysis with alteplase) and an observation group (combined with endovascular thrombectomy) according to different treatment methods,with 40 cases in each group.Compare the clinical efficacy,vascular recanalization rate,neurological function[National Institutes of Health Stroke Scale (NIHSS)],activities of daily living (ADL),and peak systolic velocity between two groups.Results The vascular recanalization rate (90.00％) and clinical total effective rate (97.50％) in the observation group were higher than the control group (10.00％,75.00％,P<0.05);After treatment,the NIHSS score (19.96±2.48) of the observation group was lower than the control group (22.60±3.02),and the ADL score (84.89±6.20) was higher than the control group (78.79±5.78) (P<0.05);After treatment,the peak systolic velocity levels of the common carotid artery (110.08±12.05) cm/s,internal carotid artery (112.17±18.25) cm/s,vertebral artery (112.16±17.60) cm/s,and basilar artery (116.63±8.69) cm/s in the observation group were lower than those in the control group (140.06±18.87),(218.87±20.46),(200.03±20.04),and (202.03±12.05) cm/s (P<0.05).Conclusion The implementation of intravascular thrombectomy combined with alteplase intravenous thrombolysis has significnat efficacy on elderly patients with ACI,which can improve vascular recanalization rate,improve neurological function and daily living ability,and reduce the risk of vascular restenosis.
Old ageAcute cerebral infarctionAlteplaseIntravascular thrombectomyIntravenous thrombolysisNeurological function
万方数据
维普
