Study on the correlation of blood lipid indicators with traditional Chinese medicine constitutions in elderly people with hyperlipemia
Objective To explore the correlation of blood lipid indicators with traditional Chinese medicine constitutions in elderly people with hyperlipemia (HP),so as to provide basis for clinical treatment.Methods 600 elderly patients with HP were selected,and their blood lipid indicators were measured using the Mindray BS-830 detector to classify their traditional Chinese medicine constitutions.The basic conditions and lipid indicators of patients with different traditional Chinese medicine constitutions were compared,and the correlation of HP with traditional Chinese medicine constitutions was analyzed by binary Logistic regression model.Results Through clinical differentiation,among 600 elderly patients with HP,there were 60 cases (10.0%) of peaceful constitution,135 cases (22.5%) of Qi-deficiency constitution,135 cases (22.5%) of Yang-deficiency constitution,90 cases (15.0%) of Yin-deficiency constitution,75 cases (12.5%) of phlegm-damp constitution,34 cases (5.7%) of damp-heat constitution,51 cases (8.5%) of blood-stasis constitution,20 cases (3.3%) of Qi-depression constitution,and 0 cases of special constitution.There were no significant differences in gender,age,course of disease,body mass and smoking history among patients with different traditional Chinese medicine constitutions (P>0.05).The differences in total cholesterol (TC),triglycerides (TG),high-density lipoprotein cholesterol (HDL-C),and low-density lipoprotein cholesterol (LDL-C) were not statistically significant among the patients with different traditional Chinese medicine constitutions (P>0.05).TC of patients with Qi-deficiency,Yin-deficiency,damp-heat and blood-stasis constitutions were (5.14±1.21),(5.10±1.14),(5.25±1.12) and (5.45±1.31) mmol/L,and LDL-C were (2.94±0.66),(2.95±0.60),(2.95±0.53) and (3.51±1.03) mmol/L,which were all higher than (4.18±1.20) and (2.60±0.74) mmol/L of patients with peaceful constitution,and the difference was statistically significant (P<0.05).TG of patients with Qi-deficiency,Yin-deficiency,phlegm-damp,damp-heat,and blood-stasis constitutions were (2.26±0.37),(2.27±0.32),(1.87±0.45),(2.03±0.19),and (2.41±0.55) mmol/L,which were higher than (1.68±0.53) mmol/L of patients with peaceful constitution,and the difference was statistically significant (P<0.05).Binary Logistic regression analysis with HP as the dependent variable and traditional Chinese medicine constitutions as the independent variable (peaceful constitution as the reference) revealed that Qi-deficiency,Yin-deficiency,phlegm-damp,and blood-stasis constitutions are the high-risk factors for HP (P<0.05).Conclusion The blood lipid indicators of the elderly HP patients with different traditional Chinese medicine constitutions are different,and clinically,Qi-deficiency,Yin-deficiency,phlegm-damp,blood stasis and other constitutions are common.
HyperlipidemiaBlood lipidTraditional Chinese medicine constitutions