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清肺口服液结合西药常规治疗儿童支气管肺炎的效果

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目的 观察清肺口服液结合西药常规治疗儿童支气管肺炎的效果,并探索其作用机制。方法 92 例支气管肺炎患儿,以随机数字表法(1∶1 比例)分为对照组和观察组,每组 46 例。对照组患儿予以西药常规治疗,观察组患儿在对照组基础上加用清肺口服液治疗。比较两组患儿治疗前后中医证候(壮热不退、呼吸急促、咳嗽、喉间痰鸣、痰液粘稠)积分,血常规指标[白细胞计数(WBC)、淋巴细胞(LYM)百分比、中性粒细胞(NEU)百分比],临床效果及不良反应发生情况。结果 治疗后,两组患儿壮热不退、呼吸急促、咳嗽、喉间痰鸣、痰液粘稠积分均低于本组治疗前,且观察组患儿壮热不退积分(0。53±0。17)分、呼吸急促积分(0。43±0。11)分、咳嗽积分(0。37±0。14)分、喉间痰鸣积分(0。96±0。41)分、痰液粘稠积分(1。16±0。28)分与对照组的(0。96±0。23)、(0。85±0。17)、(0。72±0。17)、(1。39±0。45)、(1。69±0。35)分相比更低,有显著差异(P<0。05)。治疗后,两组患儿WBC和NEU百分比低于本组治疗前,LYM百分比高于本组治疗前,且观察组患儿WBC(5。14±0。72)×109/L、NEU百分比(51。86±4。15)%与对照组的(6。86±0。95)×109/L、(57。38±4。68)%相比更低,LYM百分比(27。53±3。73)%与对照组的(20。36±3。59)%相比更高,有显著差异(P<0。05)。观察组患儿临床总有效率 95。65%高于对照组的 82。61%,有显著差异(P<0。05)。两组患儿不良反应发生率比较,无显著差异(P>0。05)。结论 清肺口服液结合西药常规治疗儿童支气管肺炎临床效果突出,能缓解症状,控制病情,安全可靠。
The effect of Qingfei oral liquid combined with conventional Western medicine in the treatment of bronchial pneumonia in children
Objective To observe the effect of Qingfei oral liquid combined with conventional Western medicine in the treatment of bronchial pneumonia in children,and explore its mechanism.Methods 92 children with bronchial pneumonia were divided into a control group and an observation group according to random numerical table(1∶1 ratio),each consisting of 46 cases.The control group was treated with conventional Western medicine,and the observation group was treated with Qingfei oral liquid based on the control group.Both groups were compared in terms of traditional Chinese medicine syndrome score(persistent heat,shortness of breath,cough,sputum ringing in larynx,thick sputum),blood routine indicators[white blood cell count(WBC),lymphocyte(LYM)percentage,neutrophil(NEU)percentage],clinical effect,and occurrence of adverse reactions.Results After treatment,the scores of persistent heat,shortness of breath,cough,sputum ringing in larynx and thick sputum in both groups were lower than those before treatment;in the observation group,the score of persistent heat was(0.53±0.17)points,the score of shortness of breath was(0.43±0.11)points,the score of cough was(0.37±0.14)points,the score of sputum ringing in larynx was(0.96±0.41)points and the score of thick sputum was(1.16±0.28)points,which were higher than(0.96±0.23),(0.85±0.17),(0.72±0.17),(1.39±0.45)and(1.69±0.35)points in the control group;there were significant differences(P<0.05).After treatment,the WBC and NEU percentage in both groups were lower than those before treatment,while the LYM percentage was higher than that before treatment;the observation group had WBC of(5.14±0.72)×109/L and NEU percentage of(51.86±4.15)%,which were lower than(6.86±0.95)×109/L and(57.38±4.68)%in the control group;LYM percentage of(27.53±3.73)%in the observation group was higher than(20.36±3.59)%in the control group;there were significant differences(P<0.05).The total clinical effective rate of 95.65%in the observation group was higher than 82.61%in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The clinical effect of Qingfei oral liquid combined with conventional Western medicine in the treatment of children with bronchial pneumonia is outstanding,which can relieve symptoms and control the condition,and is safe and reliable.

Qingfei oral liquidBronchial pneumonia in childrenTraditional Chinese medicine syndromeBlood routine indicatorsEffect

祁陆石

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210004 江苏省中医院儿科

清肺口服液 儿童支气管肺炎 中医证候 血常规指标 效果

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(22)