Investigation and analysis of clinical and etiologic characteristics of viral pneumonia patients with chronic obstructive pulmonary disease
Objective To study the clinical and etiologic characteristics of viral pneumonia patients with chronic obstructive pulmonary disease.Methods A total of 202 patients with viral pneumonia were selected and divided into a chronic obstructive pulmonary disease group(50 patients with viral pneumonia and chronic obstructive pulmonary disease)and a non-chronic obstructive pulmonary disease group(152 patients with simple viral pneumonia)according to the relevant diagnostic criteria in the Global Creation Guidelines for Chronic Obstructive Pulmonary Disease.Both groups were tested and compared for clinical characteristics[age,gender,body mass index(BMI),smoking,underlying diseases(hypertension,diabetes mellitus,cardiovascular disease,cerebrovascular disease),clinical symptoms(fever,cough,sputum,dyspnea)],laboratory parameters[white blood cell count(WBC),lymphocyte count,procalcitonin(PCT),C-reactive protein(CRP),hemoglobin,ratio of forced expiratory volume in one second to forced vital capacity(FEV1/FVC),oxygen saturation,pH value],pathogenetic test results,length of hospitalization for rehabilitation,and mortality.Results The age of(76.12±3.49)years in chronic obstructive pulmonary disease group was greater than(67.45±3.11)years in non-chronic obstructive pulmonary disease group,while BMI of(18.91±2.02)kg/m2 was lower than(23.65±3.10)kg/m2 in non-chronic obstructive pulmonary disease group(P<0.05).The percentages of hypertension,cardiovascular disease,and cough and dyspnea were 68.00%,52.00%,98.00%,and 50.00%in chronic obstructive pulmonary disease group,which were higher than 50.66%,33.55%,88.16%,and 27.63%in non-chronic obstructive pulmonary disease group(P<0.05).CRP of(65.27±10.35)mg/L in chronic obstructive pulmonary disease group was higher than(44.79±4.62)mg/L in non-chronic obstructive pulmonary disease group,whereas FEV1/FVC of(61.59±5.23)%was lower than(79.68±5.75)%in non-chronic obstructive pulmonary disease group(P<0.05).The percentage of comorbid bacterial infections in chronic obstructive pulmonary disease group was 56.00%,which was higher than 32.89%in non-chronic obstructive pulmonary disease group(P<0.05).The difference between the two groups was not significant when comparing the percentage of influenza virus infection,other viral infection and combined atypical pathogen infection(P>0.05).The length of hospitalization for rehabilitation of(13.42±2.11)d in chronic obstructive pulmonary disease group was longer than(8.51±1.35)d in non-chronic obstructive pulmonary disease group,and the mortality rate of 22.00%(11/50)was higher than 5.92%(9/152)in non-chronic obstructive pulmonary disease group(P<0.05).Conclusion Patients with viral pneumonia and chronic obstructive pulmonary disease are generally older,tend to have a lower BMI,a poorer lung function,and a higher incidence of comorbid hypertension,cardiovascular disease,sputum,dyspnea,and a higher risk of comorbid bacterial infections.
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