Effect of Helicobacter pylori infection on blood glucose and lipids in women with gestational diabete
Objective To observe the effect of Helicobacter pylori infection on blood glucose and lipids in women with gestational diabete.Methods 84 cases of women with gestational diabetes were selected.According to whether there was Helicobacter pylori infection,they were divided into a control group(with infection)and a study group(without infection),with 42 cases in each group.The blood glucose indicators[fasting blood glucose,2 h postprandial blood glucose,glycated hemoglobin],blood lipid indicators[total cholesterol(TC),triglycerides(TG),low density lipoprotein cholesterol(LDL-C)]and pregnancy outcome were compared between the two groups.Results In the study group,the fasting blood glucose,2 h postprandial glucose,glycated hemoglobin,TC,TG and LDL-C were(8.48±2.04)mmol/L,(10.68±2.27)mmol/L,(8.76±1.33)%,(6.71±1.32)mmol/L,(3.43±0.58)mmol/L and(3.53±0.53)mmol/L,which were higher than(7.28±1.18)mmol/L,(8.60±1.20)mmol/L,(7.35±0.96)%,(3.05±0.74)mmol/L,(2.27±0.31)mmol/L and(2.83±0.55)mmol/L in the control group,and there were significant differences between the two groups(P<0.05).In the study group,the incidence of cesarean section,pre-eclampsia,postpartum hemorrhage,neonatal respiratory distress syndrome,macrosomia and low-birth-weight infants were 52.38%,19.05%,21.43%,19.05%,19.05%and 21.43%,which were higher than 30.95%,2.38%,4.76%,2.38%,2.38%and 2.38%in the control group,and there was significant difference between the two groups(P<0.05).Conclusion In patients with gestational diabetes,Helicobacter pylori infection has a greater impact on blood glucose and lipid levels,and increases the rate of cesarean section,as well as pre-eclampsia,postpartum hemorrhage,neonatal respiratory distress syndrome,macrosomia,and low-birth-weight infants.Therefore,for patients with gestational diabetes,early detection of Helicobacter pylori should be carried out to clarify their infection,so as to implement early intervention and improve pregnancy outcomes.
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