Observation on clinical effect of intermittent and continuous blue light irradiation the treatment of neonatal jaundice
Objective To compare the clinical effect and safety of intermittent and continuous blue light irradiation the treatment of neonatal jaundice.Methods 92 cases of neonatal jaundice were divided into an observation group and a control group by random number table method,with 46 cases in each group.The control group received continuous blue light irradiation,and the observation group received intermittent blue light irradiation.The clinical efficacy,total bilirubin level,clinical indicators and adverse reactions were compared between the two groups.Results There was no significant difference in total effective rate between the observation group and the control group(P>0.05).After 1,2 and 3 d of treatment,the total bilirubin levels in the observation group were(165.58±10.24),(152.56±8.59)and(100.52±7.64)μmol/L,which were significantly lower than(190.96±10.48),(168.84±8.52)and(117.48±6.59)μmol/L in the control group,and the difference was statistically significant(P<0.05).In the observation group,the disappearance time of jaundice symptoms was(4.52±1.03)d,which was shorter than(6.85±1.08)d in the control group;the sleeping time was(18.59±1.03)h/d,which was longer than(15.54±1.74)h/d in the control group;the frequency of crying was(3.56±0.38)/d,which was less than(5.25±0.84)/d in the control group;the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 2.17%,which was lower than 13.04%in the control group,and the difference was statistically significant(P<0.05).Conclusion In the clinical treatment of neonatal jaundice,both continuous and intermittent blue light irradiation can achieve better results,but in comparison,intermittent blue light irradiation can guarantee the safety of the treatment based on the reduction of the total bilirubin level,reduce the frequency of crying of the children,and ensure adequate sleep,so it is worth promoting.
Intermittent blue light irradiationContinuous blue light irradiationNeonatal jaundiceClinical efficacyTotal bilirubin