儿童细菌感染性疾病应用CRP+血常规检验的诊断效果分析

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中文摘要：目的观察儿童细菌感染性疾病应用C反应蛋白(CRP)+血常规检验的诊断效果.方法选取 200 例疑似细菌感染性疾病患儿作为研究对象,均接受CRP、血常规检验.以细菌培养作为"金标准",分析"金标准"的诊断结果;比较"金标准"检出的阳性和阴性患儿CRP、血常规指标水平;分析CRP、血常规单独检验及CRP+血常规检验的诊断结果;比较CRP、血常规单独检验及CRP+血常规检验的诊断效能.结果"金标准"诊断结果显示:阳性163例(81.50%),阴性37例(18.50%)."金标准"阳性患儿CRP(13.65±1.02)mg/L、白细胞计数(24.11±4.57)×109/L及中性粒细胞数(8.53±0.75)×109/L均高于"金标准"阴性患儿的(8.09±1.45)mg/L、(7.55±1.67)×109/L、(5.06±0.58)×109/L,差异具有统计学意义(P<0.05).CRP单独检验阳性 159 例,阴性 41 例;血常规单独检验阳性 145 例,阴性 55 例;CRP+血常规检验阳性 162 例,阴性 38 例.CRP+血常规检验的诊断敏感性 98.77%、特异性 97.30%、阳性预测值 99.38%、阴性预测值 94.74%均高于CRP单独检验的 88.96%、62.16%、91.19%、56.10%及血常规单独检验的 80.37%、62.16%、90.34%、41.82%,差异有统计学意义(P<0.05).结论对细菌感染性疾病患儿进行CRP+血常规检验可尽早确诊,对治疗方案的制定具有较高的指导意义.

外文标题：Analysis of the diagnostic effect of CRP+blood routine test in children with bacterial infectious diseases

外文摘要：Objective To observe the diagnostic effect of C-reactive protein(CRP)+blood routine test in children with bacterial infectious diseases.Methods 200 children with suspected bacterial infectious diseases were selected as study subjects,and all of them received CRP+blood routine test.Using bacterial culture as the"gold standard",the diagnostic results of the"gold standard"were analyzed.The CRP and blood routine indicators were compared between"gold standard"positive and negative children.The diagnostic results of CRP,blood routine test alone and CRP+blood routine test were analyzed.The diagnostic efficacy of CRP,blood routine test alone and CRP+blood routine test was compared.Results In the"gold standard"of clinical diagnosis,163 cases(81.50%)were positive and 37 cases(18.50%)were negative.The CRP of"gold standard"positive children was(13.65±1.02)mg/L,thevwhite blood cell count was(24.11±4.57)×109/L,and the neutrophil count was(8.53±0.75)×109/L,which were higher than(8.09±1.45)mg/L,(7.55±1.67)×109/L,and(5.06±0.58)×109/L in"gold standard"negative children,and the differences were statistically significant(P<0.05).CRP was positive in 159 cases and negative in 41 cases;blood routine tests were positive in 145 cases and negative in 55 cases;CRP+blood routine tests were positive in 162 cases and negative in 38 cases.The diagnostic sensitivity of CRP+blood routine test was 98.77%,the specificity was 97.30%,the positive predictive value was 99.38%and the negative predictive value was 94.74%,which were higher than 88.96%,62.16%,91.19%and 56.10%of CRP alone,and 80.37%,62.16%,90.34%,41.82%of blood routine tests alone.The difference was statistically significant(P<0.05).Conclusion CRP+blood routine test can be used for early diagnosis of bacterial infectious diseases in children,which has a high clinical significance for the formulation of treatment plans.

外文关键词：

Bacterial infectious diseases in childrenC-reactive proteinBlood routine testClinical diagnosis

作者：

赖丽贤、江永欣、黄沉

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作者单位：

363000 漳州正兴医院

关键词：

儿童细菌感染性疾病 C反应蛋白血常规检验临床诊断

出版年：

2024

DOI：