首页|宫腔镜下诊刮术联合曼月乐治疗围绝经期异常子宫出血的疗效观察

宫腔镜下诊刮术联合曼月乐治疗围绝经期异常子宫出血的疗效观察

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目的 探究宫腔镜下诊刮术结合左炔诺孕酮宫内节育系统(商品名:曼月乐)治疗围绝经期异常子宫出血(AUB)患者的临床疗效。方法 62 例围绝经期异常子宫出血患者,根据治疗方法不同分为对照组和观察组,每组 31 例。对照组使用宫腔镜下诊刮术治疗,观察组使用宫腔镜下诊刮术联合曼月乐治疗。比较两组患者的治疗效果、子宫内膜厚度、血红蛋白(Hb)水平以及并发症发生情况。结果 观察组治疗总有效率 93。55%较对照组的 74。19%高,差异显著(P<0。05)。治疗后,两组子宫内膜厚度低于本组治疗前,Hb水平高于本组治疗前,且观察组子宫内膜厚度(5。51±0。36)mm较对照组的(6。58±0。65)mm低,Hb(98。63±4。22)g/L较对照组的(87。30±3。54)g/L高,差异显著(P<0。05)。观察组并发症发生率 16。13%较对照组的 41。94%低,差异显著(P<0。05)。结论 宫腔镜下诊刮术结合曼月乐治疗围绝经期异常子宫出血患者效果显著,不仅可提高患者的Hb水平,还可积极改善其子宫内膜厚度,减少后续并发症的出现。
Clinical observation of hysteroscopic curettage combined with Mirena in the treatment of perimenopausal abnormal uterine bleeding
Objective To explore the clinical efficacy of hysteroscopic curettage combined with levonorgestrel intrauterine system(trade name:Mirena)in the treatment of perimenopausal abnormal uterine bleeding.Methods A total of 62 patients with perimenopausal abnormal uterine bleeding(AUB)were divided into the control group and the observation group according to different treatment methods,with 31 cases in each group.The control group was treated with hysteroscopic curettage,and the observation group was treated with hysteroscopic curettage and Mirena.The therapeutic effect,endometrial thickness,hemoglobin(Hb)level and occurrence of complications were compared between the two groups.Results The total effective rate of 93.55%in the observation group was higher than 74.19%in the control group,and the difference was significant(P<0.05).After treatment,the endometrial thickness in both groups was lower than that before treatment,and Hb level was higher than that before treatment;the observation group had lower endometrial thickness of(5.51±0.36)mm than(6.58±0.65)mm in the control group,and higher Hb of(98.63±4.22)g/L than(87.30±3.54)g/L in the control group;the difference was significant(P<0.05).The complication rate of 16.13%in the observation group was lower than 41.94%in the control group,and the difference was significant(P<0.05).Conclusion Hysteroscopic curettage combined with Mirena is significantly effective in the treatment of patients with perimenopausal abnormal uterine bleeding.It can not only increase the Hb level,but also improve the endometrial thickness,and reduce the occurrence of subsequent recurrence.

Perimenopausal periodAbnormal uterine bleedingDiagnostic curettageLevonorgestrel intrauterine systemEffectivenessSecurity

王润芝、黄晓颖

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264200 青岛大学附属威海市立第二医院药剂科

围绝经期 异常子宫出血 诊刮术 左炔诺孕酮宫内节育系统 有效性 安全性

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(22)