Study on the correlation between blood routine NLR,MLR,PLR and severity of coronary artery stenosis in patients with coronary heart disease
Objective To analyze the correlation between blood routine neutrophil-to-lymphocyte ratio (NLR),monocyte-to-lymphocyte ratio (MLR),platelet-to-lymphocyte ratio (PLR) and severity of coronary artery stenosis in patients with coronary heart disease. Methods 408 patients with coronary heart disease were selected as the observation group,and another 408 healthy subjects who underwent health examination during the same period were selected as the control group. The blood routine of the two groups was detected,and the levels of NLR,MLR and PLR were calculated and compared between the two groups. All patients in the observation group underwent coronary angiography and were divided into mild lesion group (156 cases),moderate lesion group (123 cases) and severe lesion group (129 cases) according to the severity of coronary artery stenosis (Gensini score). The levels of NLR,MLR and PLR were compared in subgroups of the observation group,and the correlation of NLR,MLR and PLR with the severity of coronary artery stenosis in patients with coronary heart disease was analyzed. Results The levels of NLR,MLR and PLR were (4.64±1.43),(0.39±0.12) and (157.73±42.58) in the observation group,which were higher than (2.38±0.71),(0.28±0.09) and (124.25±37.69) in the control group,and the difference was statistically significant (P<0.05). There were significant differences in levels of NLR,MLR and PLR among all subgroups in the observation group (P<0.05). The levels NLR,MLR and PLR in the severe lesion group were higher than those in the moderate lesion group and the mild lesion group,and the moderate lesion group were higher than the mild lesion group. The difference was statistically significant (P<0.05). The difference was statistically significant (P<0.05). The results of correlation analysis showed that the levels of NLR,MLR and PLR were positively correlated with the Gensini score in patients with coronary heart disease (r=0.687,0.622,0.416;P<0.001). Conclusion The levels of NLR,MLR,and PLR in patients with coronary heart disease were higher than those in healthy individuals,and the levels of these indicators in patients with coronary heart disease are positively correlated with the severity of coronary artery stenosis.
Neutrophil-to-lymphocyte ratioMonocyte-to-lymphocyte ratioPlatelet-to-lymphocyte ratioCoronary heart diseaseSeverity of coronary artery stenosis
万方数据
维普
