Effect analysis of different modes of ventilator-assisted ventilation in ICU patients with acute exacerbation of chronic obstructive pulmonary disease and respiratory failure
Objective To explore the effect of different modes of ventilator-assisted ventilation in intensive care unit (ICU) patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and respiratory failure (RF). Methods 56 patients with AECOPD and RF in ICU were selected and divided into a control group and an observation group according to different modes of ventilator-assisted ventilation,each consisting of 28 cases. The control group was treated with invasive ventilator-assisted ventilation,and the observation group was treated with sequential invasive-noninvasive mechanical ventilation. Patients in both groups were compared in terms of efficacy,heart rate,respiratory rate,blood gas analysis indexes[blood oxygen saturation (SaO2),arterial partial pressure of oxygen (PaO2),arterial partial pressure of carbon dioxide (PaCO2)]and quality of life. Results The total effective rate of 92.86％ in the observation group was higher than 67.86％ in the control group,and the difference was significant (P<0.05). After treatment,the observation group had heart rate of (85.32±6.28) beats/min,respiratory rate of (19.35±3.25) times/min,and PaCO2 (42.36±5.05) mm Hg (1 mm Hg=0.133 kPa),which were lower than (93.02±6.81) beats/min,(25.61±3.51) times/min,and (46.65±6.42) mm Hg in the control group;the observation group had PaO2 of (93.52±3.84) mm Hg and SaO2 of (82.51±5.86)％,which were higher than (89.25±4.11) mm Hg and (76.35±6.24)％ in the control group;the difference was significant (P<0.05). After treatment,the physical score of the observation group was (64.42±3.57) points,the psychological score was (63.78±3.55) points,the social score was (66.33±4.37) points and the environmental score was (69.54±4.55) points,which were higher than (60.84±4.76),(60.83±4.78),(62.47±5.45) and (64.24±5.36) points of the control group,and the difference was significant (P<0.05). Conclusion Compared with invasive mechanical ventilation alone,sequential invasive-noninvasive mechanical ventilation therapy for ICU patients with AECOPD and RF can better improve the heart rate,respiratory rate and blood gas analysis indicators,thereby improving the clinical effect and further improving the quality of life of patients,which is worthy of application.
Acute exacerbation of chronic obstructive pulmonary diseaseRespiratory failureInvasive mechanical ventilationNon invasive mechanical ventilationBlood gas analysis indicatorsQuality of life
万方数据
维普
