Effect of magnesium sulfate and phloroglucinol on fetal preservation and inflammation markers in pregnant women with threatened abortion
Objective To explore the effect of magnesium sulfate and phloroglucinol on fetal preservation and inflammation markers[C-reactive protein (CRP) and procalcitonin (PCT)]in pregnant women with threatened abortion. Methods 100 pregnant women with threatened abortion were selected and randomly divided into a control group and an observation group,with 50 cases in each group. The control group was treated with magnesium sulfate,and the observation group was treated with phloroglucinol. The symptoms disappearance time,effect of fetal preservation,adverse reactions after medication,and the levels of CRP and PCT before and after treatment were compared between the two groups. Results The disappearance time of uterine contraction,vaginal bleeding,back pain and abdominal pain were (21.49±6.72),(28.34±5.08),(36.21±9.32) and (56.45±10.75) h in the observation group,which were significantly shorter than (27.84±7.97),(36.46±8.53),(49.88±11.64) and (64.62±12.95) h in the control group (P<0.05). The overall effective rate of fetal preservation was 90.00％ in the observation group,which was significantly higher than 74.00％ in the control group (P<0.05). After treatment,the levels of CRP and PCT in both groups were lower than those before treatment;the observation group had CRP of (4.15±0.72) mg/L and PCT of (0.65±0.22) ng/ml,which were significantly lower than (4.74±0.87) mg/L and (0.77±0.31) ng/ml in the control group (P<0.05). The incidence of adverse reactions after medication was 12.00％ in the observation group,which was significantly lower than 28.00％ in the control group (P<0.05). Conclusion Compared with magnesium sulfate,phloroglucinol has a better effect on fetal protection in pregnant women with threatened abortion,which can quickly relieve their clinical symptoms,reduce the levels of CRP and PCT,and the incidence of adverse reactions is low.
Threatened abortionMagnesium sulfatePhloroglucinolEffect of fetal preservationInflammatory markers
万方数据
维普
