The effect of Fuzheng Xiaoliu decoction on immune function and long-term curative effect of postoperative patients with breast cancer
Objective To observe the effect of Fuzheng Xiaoliu decoction on immune function and long-term curative effect of postoperative patients with breast cancer. Methods 50 postoperative patients with breast cancer were divided into an observation group and a control group according to random numerical table,with 25 cases in each group. The control group received adjuvant chemotherapy within 3 weeks after operation,and the observation group was treated with Fuzheng Xiaoliu decoction on the basis of the control group. The therapeutic effect,metastasis rate,local recurrence rate,traditional Chinese medicine syndrome score,serum tumor markers and immune function indexes after treatment were compared between the two groups. Results In the observation group,the total effective rate was 92.00％,the metastasis rate was 12.00％ and the local recurrence rate was 12.00％;in the control group,the total effective rate was 68.00％,the metastasis rate was 36.00％ and the local recurrence rate was 36.00％. The total effective rate of treatment in the observation group was significantly higher than that in the control group,and the metastasis rate and local recurrence rate were significantly lower than those in the control group. The difference was statistically significant (P<0.05). After treatment,the scores of fatigue,insomnia,dry mouth,sweating and breast tenderness in the observation group were significantly lower than those in the control group,and the difference was statistically significant (P<0.05). After treatment,the levels of CEA,CA125 and CA153 in the observation group were (2.98±1.30) μg/L,(18.02±6.13) U/ml and (13.72±3.58) U/ml,which were significantly lower than (4.64±2.17) μg/L,(29.75±8.61) U/ml and (21.85±7.46) U/ml in the control group,and the difference was statistically significant (P<0.05). After treatment,the observation group had CD3+of (1250±200) cells/μl,CD4+of (850±150) cells/μl,and CD4+/CD8+of (2.1±0.4),which were significantly higher than (1050±180) cells/μl,(700±120) cells/μl,and (1.7±0.3) in the control group;the difference was statistically significant (P<0.05). Conclusion Compared with chemotherapy alone,the combined use of chemotherapy and Fuzheng Xiaoliu Decoction can reduce the discomfort symptoms,increase the level of immunity and decrease the concentration of tumor markers in serum,reduce metastasis and recurrence,and the effect is significant,which can be popularized.
Breast cancerFuzheng Xiaoliu decoctionChemotherapyImmune functionTumor markersLong-term curative effect
万方数据
维普
