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针灸联合氯吡格雷对脑梗死后遗症患者神经功能的影响

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目的 探讨针灸联合氯吡格雷对脑梗死后遗症患者神经功能的影响。方法 选取 100 例脑梗死后遗症患者,使用随机数表法分为观察组与对照组,每组 50 例。对照组患者接受常规对症治疗,并依据指南使用氯吡格雷;观察组患者在对照组的基础上加用针灸治疗。比较两组患者的神经功能缺损程度、肢体运动障碍程度及不良事件发生情况。结果 治疗后,两组患者的美国国立卫生研究院卒中量表(NIHSS)评分均较治疗前显著下降,且观察组患者的NIHSS评分(7。54±1。34)分显著低于对照组的(11。80±2。17)分(P<0。05)。治疗后,两组患者的Fugl-Meyer肢体运动功能评定量表(FMA)评分均较治疗前显著提高,且观察组的FMA评分(89。07±10。32)分显著高于对照组的(75。62±7。44)分(P<0。05)。治疗后,对照组患者的不良事件发生率为 8。00%,观察组患者的不良事件发生率为 6。00%,两组患者不良事件发生率比较并未展现出显著的统计学差异(P>0。05)。结论 针对脑梗死后遗症患者,在常规对症治疗和氯吡格雷干预的基础上联合使用针灸干预,能够有效改善神经功能缺损程度和肢体运动障碍程度,且不会增加不良事件的发生风险,具有较好的效果和安全性,值得推广。
Effect of acupuncture combined with clopidogrel on neurological function in patients with sequelae of cerebral infarction
Objective To explore the effect of acupuncture combined with clopidogrel on neurological function in patients with sequelae of cerebral infarction.Methods 100 cases of patients with sequelae of cerebral infarction were selected and divided into the observation group and the control group using the random number table method,with 50 cases in each group.Patients in the control group received conventional symptomatic treatment and used clopidogrel according to the guidelines.Patients in the observation group were treated with acupuncture on the basis of the control group.The degree of neurological deficit,the degree of limb dyskinesia and the occurrence of adverse events of the two groups were compared.Results After treatment,the National Institutes of Health Stroke Scale(NIHSS)score in both groups was significantly decreased compared with that before treatment;NIHSS score of(7.54±1.34)points in the observation group was significantly lower than(11.80±2.17)points in the control group(P<0.05).After treatment,the score of Fugl-Meyer Assessment(FMA)in both groups was significantly higher than that before treatment;FMA score in the observation group was(89.07±10.32)points,which was significantly higher than(75.62±7.44)points in the control group(P<0.05).After treatment,the incidence of adverse events was 8.00%in the control group and 6.00%in the observation group;there was no significant difference in the incidence of adverse events between the two groups(P>0.05).Conclusion For patients with sequelae of cerebral infarction,the combined use of acupuncture on the basis of conventional symptomatic treatment and clopidogrel intervention can effectively improve the degree of neurological deficits and limb dyskinesia,and does not increase the risk of adverse events,which has a better effect and safety,and is worth promoting.

AcupunctureClopidogrelSequelae of cerebral infarctionNeurological functionMotor function

庞宁、黄红芳、张紫君、郑祖斌、苏家丽、邓明华、刘小银

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510663 广州市东升医院中西医结合科

510663 广州市东升医院神经康复科

510663 广州市东升医院检验科

针灸 氯吡格雷 脑梗死后遗症 神经功能 运动功能

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(24)