Effect of acupuncture combined with clopidogrel on neurological function in patients with sequelae of cerebral infarction
Objective To explore the effect of acupuncture combined with clopidogrel on neurological function in patients with sequelae of cerebral infarction.Methods 100 cases of patients with sequelae of cerebral infarction were selected and divided into the observation group and the control group using the random number table method,with 50 cases in each group.Patients in the control group received conventional symptomatic treatment and used clopidogrel according to the guidelines.Patients in the observation group were treated with acupuncture on the basis of the control group.The degree of neurological deficit,the degree of limb dyskinesia and the occurrence of adverse events of the two groups were compared.Results After treatment,the National Institutes of Health Stroke Scale(NIHSS)score in both groups was significantly decreased compared with that before treatment;NIHSS score of(7.54±1.34)points in the observation group was significantly lower than(11.80±2.17)points in the control group(P<0.05).After treatment,the score of Fugl-Meyer Assessment(FMA)in both groups was significantly higher than that before treatment;FMA score in the observation group was(89.07±10.32)points,which was significantly higher than(75.62±7.44)points in the control group(P<0.05).After treatment,the incidence of adverse events was 8.00%in the control group and 6.00%in the observation group;there was no significant difference in the incidence of adverse events between the two groups(P>0.05).Conclusion For patients with sequelae of cerebral infarction,the combined use of acupuncture on the basis of conventional symptomatic treatment and clopidogrel intervention can effectively improve the degree of neurological deficits and limb dyskinesia,and does not increase the risk of adverse events,which has a better effect and safety,and is worth promoting.
AcupunctureClopidogrelSequelae of cerebral infarctionNeurological functionMotor function