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腹腔镜下结肠癌切除术对结肠癌的治疗效果评价

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目的 探讨腹腔镜下结肠癌切除术对结肠癌的治疗效果。方法 选取接受腹腔镜下结肠癌切除术的 30 例结肠癌患者设为研究组,另选取接受传统开腹手术的 30 例结肠癌患者设为对照组。对比两组手术情况、术后恢复时间、术后并发症发生率、术后疼痛评分、血清炎性因子。结果 两组手术时间对比未发现明显差异(P>0。05);研究组术中失血量(43。12±7。08)ml少于对照组的(194。69±45。34)ml(P<0。05)。研究组术后恢复排气、恢复排便、初次离床活动的时间及住院天数分别为(1。63±0。36)、(2。04±0。53)、(4。21±0。79)、(10。30±1。58)d,均 较 对 照 组 的(2。07±0。41)、(2。89±0。66)、(5。30±0。84)、(12。59±1。92)d更短(P<0。05)。研究组术后并发症总发生率为 0,比对照组的 20。00%更低(P<0。05)。术后第 1、2、3 天,研究组疼痛评分分别为(4。46±1。21)、(3。85±1。16)、(3。37±0。82)分,低于对照组的(6。32±1。47)、(5。74±1。31)、(4。95±1。18)分(P<0。05)。两组术后 1 d的C反应蛋白、白细胞介素-6 均比本组术前 1 d增高,但研究组比对照组低(P<0。05)。结论 对于结肠癌患者,相较于传统开腹手术治疗,选择腹腔镜下结肠癌切除术具有更多的优势,如减轻手术创伤、术后炎症反应和疼痛感,减少术后并发症等,有助于加快手术后患者康复进展。
Evaluation of the therapeutic effect of laparoscopic resection of colon cancer for colon cancer
Objective To explore the therapeutic effect of laparoscopic resection of colon cancer for colon cancer.Methods 30 cases of colon cancer patients who underwent laparoscopic resection of colon cancer were selected as the study group,and 30 cases of colon cancer patients who underwent traditional open surgery were selected as the control group.The surgical outcomes,postoperative recovery time,incidence of postoperative complications,postoperative pain score,and serum inflammatory factors were compared between two groups.Results Regarding the surgical time,no significant difference was found between the groups(P>0.05).However,the study group had less intraoperative blood loss of(43.12±7.08)ml than(194.69±45.34)ml in the control group(P<0.05).The time for postoperative recovery of exhaust,defecation,initial ambulation,and hospitalization days in the study group were(1.63±0.36),(2.04±0.53),(4.21±0.79),and(10.30±1.58)d,which were shorter than(2.07±0.41),(2.89±0.66),(5.30±0.84),and(12.59±1.92)d in the control group(P<0.05).The overall incidence of postoperative complications in the study group was 0,which was lower than 20.00%in the control group(P<0.05).On postoperative days 1,2,and 3,the pain scores in the study group were(4.46±1.21),(3.85±1.16),and(3.37±0.82)points,which were lower than(6.32±1.47),(5.74±1.31),and(4.95±1.18)points in the control group(P<0.05).The levels of C-reactive protein and interleukin-6 in both groups at 1 d postoperatively were higher than those before operation in this group,but the study group was lower than the control group(P<0.05).Conclusion Compared with the traditional open surgery,laparoscopic resection of colon cancer has more advantages in the treatment of colon cancer,such as reducing surgical trauma,alleviating postoperative inflammatory reaction and pain,and decreasing postoperative complications,which is helpful to accelerate the progress of postoperative rehabilitation of patients.

Colon cancerOpen surgeryLaparoscopic resection of colon cancerTherapeutic effect

王志超、杨广达、陈倩雅、王璟

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511300 广州医科大学附属第四医院肿瘤科

结肠癌 开腹手术 腹腔镜下结肠癌切除术 治疗效果

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(24)