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老年患者腹部手术后发生静脉血栓的危险因素分析

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目的 分析老年患者腹部手术(AS)后发生静脉血栓的危险因素。方法 临床选取 138 例进行腹部手术的老年患者的临床资料进行回顾性分析,依据患者术后临床检查结果,将发生静脉血栓的患者划分至发生组(n=35),未发生静脉血栓的患者划分至未发生组(n=103)。收集两组患者一般资料及临床特征等并进行对比,针对存在差异的指标,使用二元Logistic回归分析老年患者腹部手术后发生静脉血栓的危险因素,并绘制受试者工作特征曲线(ROC曲线),计算灵敏度、特异度、曲线下面积(AUC),观察各因素对患者术后发生静脉血栓的预测价值。结果 两组患者性别、饮酒史、家族疾病史、人均月收入、手术方式、麻醉等级、高血压史、糖尿病史、肺部感染、既往静脉血栓情况比较,无显著差异(P>0。05);发生组患者的年龄>80 岁占比 62。86%、有吸烟史占比 60。00%、术后卧床时间≥72 h占比65。71%、有肢体运动受限占比 68。57%、有术后对运动的恐惧占比 74。29%、体质量指数(BMI)≥24 kg/m2占比 57。14%、手术时间>30 min占比 62。86%均大于未发生组的 33。98%、32。04%、38。83%、37。86%、48。54%、31。07%、35。92%,存在显著差异(P<0。05)。年龄>80 岁、术后卧床时间≥72 h、有肢体运动受限、有术后对运动的恐惧、有吸烟史、BMI≥24 kg/m2、手术时间>30 min均为老年患者腹部手术后发生静脉血栓的独立危险因素(OR均>1,P<0。05)。年龄、术后卧床时间、肢体运动受限、术后对运动的恐惧、吸烟史、BMI及手术时间的AUC分别为 0。644、0。634、0。649、0。629、0。640、0。630、0。635,灵敏度分别为 0。629、0。657、0。686、0。743、0。600、0。571、0。629、特异度分别为 0。660、0。612、0。612、0。515、0。680、0。689、0。641,表明以患者年龄>80 岁、术后卧床时间≥72 h、有肢体运动受限、有术后对运动的恐惧、有吸烟史、BMI≥24 kg/m2、手术时间>30 min为依据,分别有 64。4%、63。4%、64。9%、62。9%、64。0%、63。0%、63。5%的几率预测出患者腹部手术后发生静脉血栓。结论 老年患者腹部手术后发生静脉血栓的危险因素包含年龄>80 岁、术后卧床时间≥72 h、有肢体运动受限、有术后对运动的恐惧、有吸烟史、BMI≥24 kg/m2、手术时间>30 min,各因素对患者术后发生静脉血栓的预测价值较高。
Analysis of risk factors for venous thrombosis after abdominal surgery in elderly patients
Objective To analyze the risk factors for venous thrombosis after abdominal surgery(AS)in elderly patients.Methods The clinical data of 138 elderly patients who underwent abdominal surgery were retrospectively analyzed,and based on the postoperative clinical examination results,patients who developed venous thrombosis were classified into the occurrence group(n=35),and those who did not develop venous thrombosis were classified into the non-occurrence group(n=103).The general data and clinical characteristics of the two groups of patients were collected and compared.For indicators with differences,binary Logistic regression was used to analyze the risk factors for venous thrombosis in elderly patients after abdominal surgery,and the receiver operating characteristic(ROC)curves were plotted to calculate the sensitivity,specificity and the area under the curve(AUC),and the predictive value of each factor to the occurrence of postoperative venous thrombosis was observed.Results There was no significant difference in the comparison of gender,history of alcohol consumption,family history of disease,per capita monthly income,mode of surgery,grade of anesthesia,history of hypertension,history of diabetes mellitus,pulmonary infections,and previous venous thrombosis between the two groups(P>0.05).In the occurrence group,62.86%of patients were>80 years old,60.00%had a history of smoking,65.71%had postoperative bedridden time≥72 h,68.57%had limb movement limitation,74.29%had postoperative fear of exercise,57.14%had a body mass index(BMI)of≥24 kg/m2,and 62.86%had an operation time of>30 min,which were higher than 33.98%,32.04%,38.83%,37.86%,48.54%,31.07%,and 35.92%in the non-occurrence group,and there were significant differences(P<0.05).>80 years of age,postoperative bedridden time≥72 h,limb movement limitation,postoperative fear of exercise,history of smoking,BMI≥24 kg/m2,and operation time>30 min were all independent risk factors for venous thrombosis after abdominal surgery in elderly patients(all OR>1,P<0.05).The AUCs for age,postoperative bedridden time,limb movement limitation,postoperative fear of exercise,history of smoking,BMI and operation time were 0.644,0.634,0.649,0.629,0.640,0.630 and 0.635,the sensitivities were 0.629,0.657,0.686,0.743,0.600,0.571 and 0.629,and the specificities were 0.660,0.612,0.612,0.515,0.680,0.689 and 0.641.It indicated that based on>80 years of age,postoperative bedridden time≥72 h,limb movement limitation,postoperative fear of exercise,history of smoking,BMI≥24 kg/m2 and operation time>30 min,there were 64.4%,63.4%,64.9%,62.9%,64.0%,63.0%and 63.5%chances of predicting the occurrence of venous thrombosis after abdominal surgery.Conclusion Risk factors for venous thrombosis after abdominal surgery in elderly patients include>80 years of age,postoperative bedridden time≥72 h,limb movement limitation,postoperative fear of exercise,history of smoking,BMI≥24 kg/m2,and operation time>30 min,and each factor has a high predictive value for the occurrence of postoperative venous thrombosis in patients.

AgedAbdominal surgeryVenous thrombosisRisk factors

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351100 莆田市第一医院胃肠外科一科

老年人 腹部手术 静脉血栓 危险因素

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(24)