Observation on the curative effect of modified Danzhi Xiaoyao powder in the treatment of insomnia
Objective To analyze the effect of modified Danzhi Xiaoyao powder in the treatment of insomnia.Methods 100 insomnia patients were included,and divided into control group(n=50)and study group(n=50)by closed envelope method.The control group was treated with Liuwei Dihuang pill,and the study group was treated with modified Danzhi Xiaoyao powder on the basis of the control group.The clinical efficacy,sleep quality,traditional Chinese medicine syndrome score and quality of life were compared between the two groups.Results After 1 month of treatment,the total effective rate of 98.00%in the study group was higher than 86.00%in the control group(P<0.05).Before treatment,there were no differences in comparison of scores of Pittsburgh sleep quality index(PSQI)for sleep efficiency,sleep quality,sleep latency,hypnotic drugs,sleep time,sleep disturbance and daytime dysfunction between the two groups(P>0.05).After 1 month of treatment,the PSQI scores for sleep efficiency,sleep quality,sleep latency,hypnotic drugs,sleep time,sleep disturbance and daytime dysfunction of the study group were(1.56±0.32),(1.37±0.54),(1.46±0.41),(1.02±0.34),(1.31±0.27),(1.22±0.43)and(1.46±0.23)points,which were lower than(1.93±0.45),(1.84±0.36),(1.83±0.37),(1.67±0.53),(1.86±0.42),(1.73±0.58)and(1.93±0.37)points of the control group(P<0.05).Before treatment,there was no difference in the comparison of scores of insomnia and nightmares,drowsiness,easy to wake up,irritability,and chest and rib distension pain between the two groups(P>0.05).After 1 month of treatment,the scores of insomnia and nightmares,drowsiness,easy to wake up,irritability,and chest and rib distension pain in the study group were(0.82±0.23),(0.73±0.38),(0.93±0.39),(0.77±0.19),and(0.52±0.53)points,which were lower than(1.82±0.51),(1.79±0.14),(1.95±0.47),(1.63±0.26),and(1.86±0.42)points in the control group(P<0.05).Before treatment,there was no difference in the comparison of scores of World Health Organization Quality of Life Assessment(100-item version)(WHOQOL-100)for physiology,psychology,social relationships,spiritual/religious beliefs,environment and independence between the two groups(P>0.05).After 1 month of treatment,the scores of WHOQOL-100 for physiology,psychology,social relationships,spiritual/religious beliefs,environment and independence in the study group were(96.71±3.69),(94.47±3.58),(92.38±3.47),(95.29±3.71),(95.49±3.28)and(96.28±3.55)points,which were higher than(93.82±3.81),(91.83±4.72),(89.62±3.57),(91.37±3.67),(92.83±4.67)and(93.82±3.67)points in the control group(P<0.05).Conclusion The therapeutic effect of Danzhi Xiaoyao powder combined with Liuwei Dihuang pill in the treatment of insomnia is remarkable,which can improve the treatment efficiency,reduce the traditional Chinese medicine syndrome score,thus improving the sleep quality and the quality of life of patients.
Danzhi Xiaoyao powderLiuwei Dihuang pillTraditional Chinese medicine syndrome scoreSleep qualityCalm down