Observation on the effects of conventional hemodialysis combined with high-flux hemodialysis on patients with renal failure in the uremic stage
Objective To observe the effects of conventional hemodialysis combined with high-flux hemodialysis on patients with renal failure in the uremic stage.Methods A total of 60 patients diagnosed with renal failure in the uremic stage were included in the study,and divided into conventional hemodialysis group and high-flux hemodialysis group based on the dialysis method received,with 30 cases in each group.Patients treated with conventional hemodialysis were categorized were categorized as the conventional hemodialysis group,while patients treated with both conventional and high-flux hemodialysis as the high-flux hemodialysis group.The serum indices before and after treatment and the occurrence of complications were compared between the two groups.Results After treatment,in the high-flux hemodialysis group,the urea nitrogen was(13.98±2.30)mmol/L,the creatinine was(657.48±71.09)μmol/L,the β2-microglobulin was(24.36±4.06)mg/L,the phosphorus was(2.07±0.53)mmol/L,the parathyroid hormone(PTH)was(442.47±80.53)pg/ml,and the C-reactive protein was(16.98±2.30)mg/L,which were lower than(16.51±2.28)mmol/L,(716.93±71.21)μmol/L,(30.16±4.33)mg/L,(2.42±0.79)mmol/L,(502.49±77.79)pg/ml,and(27.51±2.28)mg/L in the conventional hemodialysis group;the hemoglobin was(118.75±4.21)g/L,the total calcium was(2.69±0.11)mmol/L,and the plasma albumin was(47.71±3.86)g/L,which were higher than(113.15±4.32)g/L,(2.59±0.25)mmol/L,and(42.97±3.34)g/L in conventional hemodialysis group;the difference was statistically significant(P<0.05).The incidence of complications in the high-flux hemodialysis group was 6.67%,which was lower than 36.67%in the conventional hemodialysis group,and the difference was statistically significant(P<0.05).Conclusion Hemodialysis treatment for renal failure in the uremic stage,especially when combined with high-flux hemodialysis,can significantly improve dialysis quality,nutritional indicators,and the microinflammatory state,reduce the occurrence of complications,and enhance the quality of life of patients,achieving optimal results.