首页|常规血液透析联合高通量血液透析治疗肾功能衰竭尿毒症期患者的效果观察

常规血液透析联合高通量血液透析治疗肾功能衰竭尿毒症期患者的效果观察

扫码查看
目的 观察常规血液透析联合高通量血液透析治疗肾功能衰竭尿毒症期患者的效果。方法 将肾功能衰竭尿毒症期患者 60 例纳入研究,依据患者接受透析方式的不同分成常规透析组和高通量透析组,每组 30 例。其中以常规血液透析治疗的患者作为常规透析组,以常规血液透析联合高通量血液透析治疗的患者作为高通量透析组。比较两组治疗前后血清相关指标及并发症发生情况。结果 治疗后,高通量透析组尿素氮(13。98±2。30)mmol/L、肌酐(657。48±71。09)μmol/L、β2-微球蛋白(24。36±4。06)mg/L、磷(2。07±0。53)mmol/L、甲状旁腺激素(PTH)(442。47±80。53)pg/ml、C反应蛋白(16。98±2。30)mg/L均低于常规透析组的(16。51±2。28)mmol/L、(716。93±71。21)μmol/L、(30。16±4。33)mg/L、(2。42±0。79)mmol/L、(502。49±77。79)pg/ml、(27。51±2。28)mg/L,血红蛋白(118。75±4。21)g/L、总钙(2。69±0。11)mmol/L、血浆白蛋白(47。71±3。86)g/L均高于常规透析组的(113。15±4。32)g/L、(2。59±0。25)mmol/L、(42。97±3。34)g/L,差异有统计学意义(P<0。05)。高通量透析组并发症发生率 6。67%低于常规透析组的36。67%,差异有统计学意义(P<0。05)。结论 血液透析治疗肾功能衰竭尿毒症期,在常规血液透析基础上联合高通量血液透析治疗,可显著改善患者的透析质量、营养指标及微炎症状态,减少并发症的发生,提高患者生活质量,效果理想。
Observation on the effects of conventional hemodialysis combined with high-flux hemodialysis on patients with renal failure in the uremic stage
Objective To observe the effects of conventional hemodialysis combined with high-flux hemodialysis on patients with renal failure in the uremic stage.Methods A total of 60 patients diagnosed with renal failure in the uremic stage were included in the study,and divided into conventional hemodialysis group and high-flux hemodialysis group based on the dialysis method received,with 30 cases in each group.Patients treated with conventional hemodialysis were categorized were categorized as the conventional hemodialysis group,while patients treated with both conventional and high-flux hemodialysis as the high-flux hemodialysis group.The serum indices before and after treatment and the occurrence of complications were compared between the two groups.Results After treatment,in the high-flux hemodialysis group,the urea nitrogen was(13.98±2.30)mmol/L,the creatinine was(657.48±71.09)μmol/L,the β2-microglobulin was(24.36±4.06)mg/L,the phosphorus was(2.07±0.53)mmol/L,the parathyroid hormone(PTH)was(442.47±80.53)pg/ml,and the C-reactive protein was(16.98±2.30)mg/L,which were lower than(16.51±2.28)mmol/L,(716.93±71.21)μmol/L,(30.16±4.33)mg/L,(2.42±0.79)mmol/L,(502.49±77.79)pg/ml,and(27.51±2.28)mg/L in the conventional hemodialysis group;the hemoglobin was(118.75±4.21)g/L,the total calcium was(2.69±0.11)mmol/L,and the plasma albumin was(47.71±3.86)g/L,which were higher than(113.15±4.32)g/L,(2.59±0.25)mmol/L,and(42.97±3.34)g/L in conventional hemodialysis group;the difference was statistically significant(P<0.05).The incidence of complications in the high-flux hemodialysis group was 6.67%,which was lower than 36.67%in the conventional hemodialysis group,and the difference was statistically significant(P<0.05).Conclusion Hemodialysis treatment for renal failure in the uremic stage,especially when combined with high-flux hemodialysis,can significantly improve dialysis quality,nutritional indicators,and the microinflammatory state,reduce the occurrence of complications,and enhance the quality of life of patients,achieving optimal results.

Conventional hemodialysisHigh-flux hemodialysisRenal failureUremic stage

雷永启、温嘉莉、汪洋畅

展开 >

511873 清远市清新区人民医院

常规血液透析 高通量血液透析 肾功能衰竭 尿毒症期

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(24)