Study on the effect of modified preflushing in patients with hemoperfusion preflushing
Objective To explore the effect of modified preflushing in patients with hemoperfusion preflushing.Methods 182 cases who underwent maintenance hemodialysis+hemoperfusion were selected and randomly divided into a control group and an experimental group,each containing 91 cases.The control group was treated with conventional preflushing,while the experimental group was treated with modified preflushing.Patients in both groups were compared in terms of the completion of hemoperfusion and hemodialysis,the amount of preflushed heparin,the amount of normal saline,the duration of preflush,the coagulation grading of dialysis equipment and pipelines,and the blockage of perfusion equipment.Results The completion rate of blood perfusion in the experimental group was 100.00%,which was higher than the control group's 95.60%;The completion rate of hemodialysis was 100.00%,which was higher than the control group's 93.41%,and the differences were statistically significant(P<0.05).The experimental group had a pre flush heparin dosage of 100 mg and a physiological saline dosage of 3500 ml for blood perfusion,both of which were less than the control group's 220 mg and 4000 ml;The pre flushing time for blood perfusion in the experimental group was(25.07±1.63)minutes,which was shorter than that in the control group(45.68±1.92)minutes,and the difference was statistically significant(P<0.05).The coagulation grading of dialyzers and tubes showed that the experimental group was superior to the control group,and the difference was statistically significant(P<0.05);The incidence of perfusion obstruction in the experimental group was lower than that in the control group by 10.99%,and the difference was statistically significant(P<0.05).Conclusion In the process of hemoperfusion preflushing,the modified preflushing can reduce the risk of coagulation,alleviate the psychological burden of nurses,and reduce treatment costs.Therefore,this method should be widely promoted and applied in clinical practice.
万方数据
维普
