Effect of Zhichuanling oral liquid on clinical symptoms and inflammatory indicators in children with asthmatic bronchopneumonia
Objective To explore the effect of Zhichuanling oral liquid on clinical symptoms and inflammatory indicators in children with asthmatic bronchopneumonia.Methods 90 children with asthmatic bronchopneumonia were included,and randomly divided into a control group and an observation group,with 45 cases in each group.The control group received inhaled budesonide treatment,while the observation group received Zhichuanling oral liquid on the basis of the control group.The clinical efficacy,traditional Chinese medicine syndrome score,and inflammatory markers[interleukin-6(IL-6),high-sensitivity C-reactive protein(hs-CRP),and tumor necrosis factor-α(TNF-α)]were compared between the two groups.Results The total effective rate of 95.56%in the observation group was higher than 80.00%in the control group(P<0.05).After 7 d of treatment,the scores of cough,dyspnea,and sputum in both groups were lower than those before treatment;in the observation group,the cough score was(1.67±0.81)points,the dyspnea score was(1.45±0.92)points and the sputum score was(1.17±0.86)points,which were lower than(2.48±1.12),(2.56±1.12)and(2.58±0.98)points in the control group(P<0.05).After 7 d of treatment,the levels of TNF-α,hs-CRP and IL-6 in both groups were lower than those before treatment;the observation group had TNF-α of(70.65±7.07)μg/L,hs-CRP of(4.03±0.90)mg/L and IL-6 of(30.05±3.08)pg/ml,which were lower than(77.94±7.26)μg/L,(5.04±0.98)mg/L and(34.68±3.46)pg/ml in the control group(P<0.05).Conclusion The use of Zhichuanling oral liquid on the basis of inhaled budesonide treatment has a significant therapeutic effect in children with asthmatic bronchopneumonia,and can effectively improve the clinical symptoms and optimize the inflammatory indicators.
万方数据
维普
