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补阳还五汤治疗缺血性中风临床疗效的Meta分析

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目的 系统评价补阳还五汤治疗缺血性中风的有效性和安全性。方法 通过计算机检索中国期刊全文数据库(CNKI),检索时间为建刊~2023 年 1 月 31 日。严格按照纳入与排除标准筛选文献并进行质量评价,运用RevMan 5。3 软件对所纳入的随机对照试验(RCT)进行Meta分析。结果 共检索到 390 篇文献,对文献进行筛选后,最终纳入 10 项研究,总计包括 856 例患者。Meta分析结果表明:试验组临床总有效率高于对照组[OR=4。68,95%CI=(3。04,7。22),P<0。00001],神经功能改善程度优于对照组[OR=3。17,95%CI=(1。82,5。53),P<0。0001]。结论 现有研究证据表明,补阳还五汤加减治疗缺血性中风可明显改善临床疗效,改善神经功能。
Clinical efficacy of Buyang Huanwu Decoction in the treatment of ischemic stroke:a Meta-analysis
Objective To systematically evaluate the efficacy and safety of Buyang Huanwu Decoction in the treatment of ischemic stroke.Methods The full-text database of Chinese journals(CNKI)was searched by computer from its establishment to January 31,2023.The literature was screened and evaluated for quality in strict accordance with inclusion and exclusion criteria,and the included randomized controlled trials(RCTs)were Meta-analysed using RevMan 5.3 software.Results A total of 390 studies were retrieved and screened to include 10 studies,including a total of 856 patients.Meta-analysis results showed that the total effective rate of clinical efficacy in the experimental group was higher than that in the control group[OR=4.68,95%CI=(3.04,7.22),P<0.00001].The improvement in neurological function was better than that in the control group[OR=3.17;95%CI=(1.82,5.53);P<0.0001].Conclusion The existing research evidence shows that the treatment of ischemic stroke with modified Buyang Huanwu Decoction can significantly enhance the clinical efficacy,and improve the nerve function.

Ischemic strokeBuyang Huanwu DecoctionEfficacySafetyMeta-analysis

高众、田财军

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250014 山东中医药大学中医内科

250014 山东中医药大学第一临床医学院中医经典科

缺血性中风 补阳还五汤 有效性 安全性 Meta分析

2024

中国现代药物应用
中国水利电力医学科学技术学会

中国现代药物应用

影响因子:0.862
ISSN:1673-9523
年,卷(期):2024.18(24)