Effects of rehabilitation training on cardiopulmonary function and exercise tolerance in patients with advanced lung cancer undergoing radiotherapy
Objective To analyze the effects of rehabilitation training on cardiopulmonary function and exercise tolerance in patients with advanced lung cancer undergoing radiotherapy.Methods 100 patients with advanced lung cancer who were scheduled for radiotherapy were numbered according to the order of admission.Those with odd number were included in the rehabilitation training group,and those with even number were included in the control group,with 50 cases in each group.Both groups were treated with conventional radiotherapy for lung cancer,and the rehabilitation training group was given rehabilitation training on this basis.Both groups were compared in terms of lung function[force expiratory volume in one second(FEV1),forced vital capacity(FVC),FEV1/FVC],cardiac function[left ventricular ejection fraction(LVEF)and left ventricular end-diastolic diameter(LVEDD),ratio of early transmitral flow velocity to later transmitral flow velocity(E/A)]and exercise tolerance[6-min walking distance(6MWD),dyspnea degree,oxygen saturation(SpO2),pulse rate(PR)]before and after the intervention.Results After the intervention,FEV1(2.38±0.57)L and FVC(3.28±0.67)L in the rehabilitation training group were significantly higher than(2.11±0.53)and(2.97±0.76)L in the control group(P<0.05).The difference in FEV1/FVC between the two groups was not statistically significant(P>0.05).After the intervention,LVEF,LVEDD and E/A were significantly improved in both groups compared with those before the intervention;compared with(50.19±4.58)%,(1.21±0.20),and(55.73±4.68)mm in the control group,LVEF(53.52±4.47)%and E/A(1.47±0.15)in the rehabilitation training group were significantly elevated,and LVEDD(53.15±3.51)mm was significantly decreased(P<0.05).After the intervention,the 6MWD,Borg score,SpO2,and PR were significantly improved in the rehabilitation training group compared with those before the intervention(P<0.05).Compared with(375.22±17.23)m,(97.14±0.87)%,(0.87±0.36)points,and(87.04±3.57)beats/min in the control group,the 6MWD(387.16±17.08)m and SpO2(98.12±0.85)%in the rehabilitation training group were significantly increased,and the Borg score(0.58±0.35)points and PR(83.02±3.86)beats/min were significantly decreased(P<0.05).Conclusion Rehabilitation exercise training can effectively improve the cardiopulmonary function and exercise tolerance of patients with advanced lung cancer.
万方数据
维普
