Objective To explore and summarize the real experience of Peripherally Inserted Central Venous Catheters(PICC)in treating children with severe hemophilia.Methods Basic information on children with severe hemophilia A who were treated with PICC at Beijing Children's Hospital of Capital Medical University from January 2020 to December 2023 was retrospectively collected.The current treatment status of these children and data on PICC-related complications were obtained through telephone interviews and other methods.Results Seventy-six children with severe haemophilia A were enrolled in this study,with a median age of 4.2(2.3,5.8)years.123 PICCs were installed in 76 children,and in 54 children with inhibitors.Before PICC installation,17.1％(13/76)of the children were treated at home.After PICC installation,84.2％(64/76)of the children underwent home treatment.7.9％(6/76)of the children had a change in catheter position,10.5％(8/76)had catheter obstruction,39.5％(30/76)had a rash of the skin under the patch and around the patch,2 children had catheter-related thrombosis,5 children removed the PICC on their own,and 7 children removed the catheter on their own.Catheters were removed in 5 children,and 7 children developed catheter-related infections.Conclusions PICC placement is a practical and safe option for children with severe haemophilia A with inhibitors during ITI treatment.However,there are still deficiencies in PICC placement,such as complications such as local rash,catheter blockage,catheter slippage,catheter thrombosis and catheter-related infections still occur more frequently.The most suitable vascular access should be established for individual children with severe haemophilia.
关键词
血友病/儿童/经外周静脉穿刺中心静脉置管/并发症/家庭治疗
Key words
Haemophilia/Children/Peripherally Inserted Central Venous Catheters/Complications/Home treatment
维普
万方数据