Chinese Expert Consensus on the Diagnosis and Management Strategy of Patients With Statin Intolerance
Statin intolerance refers to a clinical phenomenon in which patients experienced one or more statin related adverse reactions after taking statins,which can be improved by reducing or stopping statin treatment,but symptoms then reappear after restarting statin medication.Statin intolerance cases are not uncommon,but there are certain confusions or misconceptions in the clinical diagnosis and management in the real world,including the lack of unified definitions and diagnostic standards,broad grasp of diagnosis and unscientific management strategies,which might hinder the scientific and rational use of statins to some extent.Based on that,this consensus comprehensively reviewed global research data on statin intolerance,referenced guidelines and consensus literature on statin intolerance in foreign countries and different regions,proposed the statin intolerance definition suitable for the Chinese population,and recommended corresponding diagnostic criteria and management strategies,aiming to improve the clinical application of statin medications and enhance the prevention and treatment level of atherosclerotic cardiovascular disease in China.