首页|药物涂层球囊治疗原发冠状动脉小血管慢性完全闭塞病变的疗效和安全性分析

药物涂层球囊治疗原发冠状动脉小血管慢性完全闭塞病变的疗效和安全性分析

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目的:评价药物涂层球囊治疗原发冠状动脉小血管慢性完全闭塞(CTO)病变的疗效和安全性.方法:连续纳入 2020 年 1 月至 2022 年 3 月仅使用药物涂层球囊治疗的原发冠状动脉小血管CTO病变患者,记录患者的一般信息、病史和手术信息,并通过电话或门诊随访记录患者主要不良心血管事件(MACE,包括心原性死亡、非致死性心肌梗死和靶血管血运重建)和冠状动脉旁路移植术(CABG)发生情况.结果:共纳入 160 例患者,开口病变 26 例(16.3%),分叉病变 42 例(26.3%),弥漫性病变 117 例(73.1%),钙化病变 87 例(54.4%).参考血管直径为(2.3±0.4)mm.住院期间,无MACE,无CABG,无急性冠状动脉血栓形成.随访(15.7±5.5)个月,1 例(0.6%)发生心原性死亡,6 例(3.8%)发生靶血管血运重建.MACE发生率为 4.4%,无CABG.结论:药物涂层球囊治疗原发冠状动脉小血管CTO病变安全有效,预后良好.
Efficacy and Safety Analysis of Drug-coated Balloon in the Treatment of De Novo Coronary Chronic Total Occlusion Lesions
Objectives:To evaluate the efficacy and safety of drug-coated balloon in the treatment of de novo coronary chronic occlusive lesions.Methods:Consecutive patients with de novo coronary chronic occlusive lesions treated with drug-coated balloons only were included in this study.The general information,medical history,and surgical information of the patients were recorded,and major adverse cardiovascular events(MACE,including cardiac death,myocardial infarction,and target vessel revascularization)were recorded by telephone or outpatient follow-up.Results:A total of 160 patients were included.There were 26 ostial lesions(16.3%),42 bifurcated lesions(26.3%),117 diffuse lesions(73.1%),and 87 calcified lesions(54.4%).The reference vessel diameter was(2.3±0.4)mm.During hospitalization,there were no acute myocardial infarction,cardiac death,target lesion revascularization,or acute coronary thrombosis.Cardiac death occurred in 1 case and target vessel revascularization occurred in 6 cases during follow-up.The MACE rate is 4.4%.Conclusions:Drug balloon therapy for de novo coronary chronic occlusive lesions is safe and effective,and the prognosis is satisfactory.

drug-coated balloonde novo lesionchronic total occlusion

刘蓉、乔树宾、崔锦刚、管浩、许浩博、刘晶、管常东

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中国医学科学院 北京协和医学院 国家心血管病中心 阜外医院 冠心病中心 ,北京 100037

药物涂层球囊 原发病变 慢性完全闭塞

2024

中国循环杂志
中国医学科学院

中国循环杂志

CSTPCD北大核心
影响因子:2.803
ISSN:1000-3614
年,卷(期):2024.39(2)
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