Pharmaceutical Recommendation on Rational Use and the Prescription Quality Evaluation of Direct Oral Anticoagulants
The traditional oral anticoagulant warfarin has a narrow therapeutic window,large individual dose variation,and is affected by many drug and dietary interactions,so it is necessary to monitor the international normalized ratio(INR)value frequently to monitor the efficacy and safety of the drug.Prescriptions for direct oral anticoagulant(DOAC)have increased rapidly because they do not require routine monitoring of coagulation function,have fewer dietary concerns,and are easy to use.Despite the many advantages of DOAC therapy,new challenges remain in the management of DOAC,including prescription inappropriateness,medication adherence requirements,potential drug interactions,and lack of specific monitoring indicators.Due to the high-risk nature of oral anticoagulants,it is necessary to improve drug safety through standardized management.The purpose of this recommendation is to provide standardized DOAC management measures and prescription review standards for physicians and pharmacists to establish DOAC-related medication safety culture.
direct oral anticoagulantsrational useprescription qualitypatient safety
万方数据
维普
