首页|经贵要静脉路径行双侧同步肾上腺静脉取血的可行性与安全性的首次报道

经贵要静脉路径行双侧同步肾上腺静脉取血的可行性与安全性的首次报道

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目的:评估经贵要静脉路径行双侧同步肾上腺静脉取血(AVS)的安全性和可行性.方法:2023 年 7 月至 2023 年 11 月连续入选中国医学科学院阜外医院经贵要静脉行双侧同步AVS的原发性醛固酮增多症(PA)患者 21 例.记录穿刺部位、选用的取血导管、手术操作时间、X线曝光时间、对比剂用量、取血成功率、不良事件及并发症发生情况.肾上腺静脉/外周静脉血浆皮质醇浓度比值≥2 定义为AVS成功.结果:21 例患者的平均年龄(49.3±7.7)岁,男性患者 13 例.所有患者右贵要静脉置入第一个 5F鞘管成功,2例无法置入第二个 5F鞘管而改用同侧头静脉.所有患者均使用 5F MPA1 导管插入右侧肾上腺静脉,5F TIG造影导管插入左侧肾上腺静脉.手术操作时间为 17.50(12.00,22.00)min,X线曝光时间为 5.90(4.75,10.55)min,对比剂用量为 25.00(25.00,35.00)ml.所有患者双侧AVS均成功.2 例患者术中出现不良事件,其中 1 例为术中导管缠绕导致 5F TIG造影导管滑出肾上腺静脉,1 例为穿刺部位血管痉挛.无手术并发症发生.结论:在大多数PA患者中经贵要静脉路径行双侧同步AVS安全可行,但需进一步验证.
The Safety and Feasibility of Simultaneous Bilateral Adrenal Vein Sampling via Basilic Vein Approach:the First Report
Objectives:To evaluate the safety and feasibility of simultaneous bilateral adrenal vein sampling(AVS)via the basilic vein approach.Methods:21 consecutive patients with primary aldosteronism(PA)who underwent simultaneous bilateral AVS via the basilic vein in Fuwai Hospital between July 2023 and November 2023 were enrolled in this study.The puncture site,catheter used in AVS,operation time,fluoroscopy time,contrast agent dosages,success rate of bilateral sampling,adverse events,and complications were recorded and analyzed.Successful sampling was determined by a selectivity index(cortisol in the adrenal vein/cortisol in inferior vena cava)greater than or equal to 2.Results:The average age of 21 patients was(49.3±7.7)years,with 13 male patients.The first 5F sheath was successfully inserted into the right basilic vein in all patients,the second 5F sheath insertion failed in two patients and switched to the ipsilateral cephalic vein approach.The 5F MPA1 catheter was inserted into the right adrenal vein and the 5F TIG catheter into the left adrenal vein in all patients.Operation time was 17.50(12.00,22.00)min,fluoroscopy time was 5.90(4.75,10.55)min,and contrast agent dosage was 25.00(25.00,35.00)ml.Bilateral AVS was successful in all patients.Two patients experienced adverse events,one case was catheter entanglement,which resulted in 5F TIG catheter slipped from adrenal vein,and another case was vascular spasm.No complications were recorded.Conclusions:Simultaneous bilateral AVS via basilic vein approach is safe and feasible in most PA patients,further researches with larger patient cohort are needed to validate the results from this study.

primary aldosteronismsimultaneous adrenal vein samplingbasilic vein approach

左毓杰、李弘武、邹玉宝、马文韬、华倚虹、董徽、蒋雄京

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中国医学科学院 北京协和医学院 国家心血管病中心 阜外医院 心内科,北京 100037

原发性醛固酮增多症 同步肾上腺静脉取血 贵要静脉路径

国家自然科学基金中国医科院医学与健康科技创新工程项目中国医科院医学与健康科技创新工程项目中央高水平医院临床科研业务费项目

817004402021-I2M-C&T-B-0262021-I2M-C&T-B-0272023-GSP-QN-10

2024

中国循环杂志
中国医学科学院

中国循环杂志

CSTPCD北大核心
影响因子:2.803
ISSN:1000-3614
年,卷(期):2024.39(8)
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