首页|因感染拔除冠状静脉左心室导线后再次植入双心室心脏再同步化治疗装置患者的临床研究

因感染拔除冠状静脉左心室导线后再次植入双心室心脏再同步化治疗装置患者的临床研究

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目的:心脏再同步化治疗患者因装置相关感染经静脉拔除冠状静脉左心室导线后再植入双心室心脏再同步化治疗(Biv-CRT)装置的策略及临床结果.方法:回顾性分析2013年1月至2022年12月在北京大学人民医院因感染经静脉行冠状静脉左心室导线拔除及再植入Biv-CRT装置的所有患者的临床资料和手术数据,并进行随访,以评估并发症发生率和全因死亡率.结果:167例患者进行了冠状静脉左心室导线拔除,161例(96.4%)拔除成功,6例(3.6%)拔除失败.拔除成功的患者,109例(67.7%)患者拟行Biv-CRT装置再植入.中位时间7(5,7)d后,行再植入Biv-CRT装置的患者6例(5.5%)失败;103例(94.5%)成功,其中102例(99.0%)通过右侧入路植入,1例(1.0%)选择左侧入路植入(因双侧均曾囊袋感染).161例拔除成功的患者中58例(36.0%)未再植入Biv-CRT装置,其中39例(24.2%)因初始适应证可疑或消失.术后1年随访期间,再植入Biv-CRT装置的103例患者共有7例(6.8%)死亡,1例(1.0%)患者囊袋感染,1例(1.0%)患者右心房导线脱位.结论:患者因感染行冠状静脉左心室导线拔除后再植入Biv-CRT装置是可行的,右侧入路植入成功率高、并发症少、死亡率低.因此,对于拔除后再评估有Biv-CRT装置植入指征的患者,应推荐进行右侧入路植入.
Effects of Reimplantation of Biventricular Cardiac Resynchronization Therapy Devices After Removal of Coronary Sinus Left Ventricular Leads due to Infections
Objectives:To evaluate the strategy and clinical outcomes of reimplanting biventricular cardiac resynchronization therapy (Biv-CRT) devices after transvenous removal of coronary sinus left ventricular leads due to device-related infections.Methods:A retrospective analysis was conducted on the clinical data and surgical outcomes of all patients who underwent transvenous removal of infectious coronary sinus left ventricular leads and subsequent reimplantation of Biv-CRT devices at Peking University People's Hospital from January 2013 to December 2022.Follow-up was performed to assess the incidence of complications and all-cause mortality.Results:A total of 167 patients underwent coronary sinus left ventricular lead removal due to infection,removal was successful in 161 cases (96.4%) and failed in 6 cases (3.6%).Among the patients with successful removal,109 cases (67.7%) were scheduled for Biv-CRT device reimplantation.After a median time of 7 (5,7) days,6 cases (5.5%) of reimplantation failed,while 103 reimplantations (94.5%) were successful.Among these successful reimplantation cases,102 patients (99.0%) were through the right-side approach,and 1 case (1.0%) through the left-side approach due to bilateral pocket infections.Of the 161 patients with successful removal,58 cases (36.0%) did not undergo left ventricular lead reimplantation,including 39 cases (24.2%) where the initial indications for Biv-CRT were questionable or had resolved.During the one-year postoperative follow-up,among the 103 patients who had undergone Biv-CRT device reimplantation,7 patients (6.8%) died,1 patient (1.0%) experienced pocket infection,and 1 patient (1.0%) had right atrial lead dislodgment.Conclusions:Reimplantation of Biv-CRT devices after removal of coronary sinus left ventricular leads due to infections is feasible,with a high success rate,low complication rate,and low mortality rate for right-side approach implantation.Therefore,for patients re-evaluated to have indications for repeated Biv-CRT after lead removal,right-side reimplantation of the coronary sinus left ventricular lead should be recommended.

cardiac resynchronization therapybiventricular cardiac resynchronization therapylead extractioncardiac device infectionreimplantationcomplication

苑翠珍、昃峰、李鼎、段江波、吴寸草、杨丹丹、李学斌

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北京大学人民医院 心内科,北京 100044

心脏再同步治疗 双心室心脏再同步治疗 导线拔除 心脏装置感染 再植入 并发症

2024

中国循环杂志
中国医学科学院

中国循环杂志

CSTPCD北大核心
影响因子:2.803
ISSN:1000-3614
年,卷(期):2024.39(11)