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心脏磁共振多参数成像评估冠心病预后的应用价值

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目的:探讨心脏磁共振多参数成像在冠心病预后评估中的应用价值.方法:回顾性分析1690例冠心病患者的心脏磁共振多参数成像图像,其中主要包括电影成像和钆对比剂延迟增强成像,电影成像用于计算左心功能及二维心肌整体纵向峰值应变,钆对比剂延迟增强成像用于判断心内膜下心肌梗死并计算梗死体积,并对所有患者进行电话随访,随访终点为发生主要不良心血管事件(MACE),MACE包括全因死亡、心力衰竭住院和心原性死亡.结果:中位随访41(37,49)个月期间,456例(27.0%)患者发生MACE.多因素Cox分析显示,左心室射血分数(HR=0.954,95%CI:0.945~0.963)、二维心肌整体纵向峰值应变(HR=1.182,95%CI:1.133~1.233)、心肌梗死体积(HR=1.037,95%CI:1.032~1.043)以及经皮冠状动脉介入治疗(HR=0.975,95%CI:0.937~0.991)、双支血管病变(HR=1.344,95%CI:1.076~1.683)、三支血管病变(HR=1.651,95%CI:1.309~2.083)均是MACE的独立预测因素(P均<0.001).结论:心脏磁共振多参数成像可评估冠心病患者预后,具有较高的临床应用价值.
The Application Value of Multi-parameter Cardiac Magnetic Resonance Imaging in Prognosis Assessment of Coronary Heart Disease
Objectives:To investigate the application value of multi-parameter cardiac magnetic resonance (CMR) imaging in evaluating the prognosis of coronary heart disease (CHD).Methods:A total of 1690 patients with CHD were retrospectively enrolled in this study.All patients underwent comprehensive CMR imaging at 3.0 T.The CMR protocols included cine imaging,and late gadolinium enhancement (LGE) imaging.All patients were followed-up by telephone.The primary endpoint was major adverse cardiovascular events (MACE),including all-cause death,heart failure related hospitalization,and cardiac death.Results:During a median follow-up of 41 (37,49) months,MACEs were recorded in 456 patients (27.0%).Multivariate Cox analysis showed that left ventricular ejection fraction (HR=0.954,95%CI:0.945-0.963),two-dimensional longitudinal peak strain (HR=1.182,95%CI:1.133-1.233),infarct volume (HR=1.037,95%CI:1.032-1.043),percutaneous coronary intervention (HR=0.975,95%CI:0.937-0.991),two-vessel disease (HR=1.344,95%CI:1.076-1.683) and three-vessel disease (HR=1.651,95%CI:1.309-2.083) were independent predictors of MACE (all P<0.001).Conclusions:CMR can be used to evaluate the prognosis in patients with CHD.

cardiovascular magnetic resonancecoronary atherosclerotic heart diseaseprognosis

李静、魏子寒、王可颜

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郑州大学第一附属医院 全科医学科,郑州 450052

郑州大学第一附属医院 磁共振科,郑州 450052

心脏磁共振成像 冠心病 预后

2024

中国循环杂志
中国医学科学院

中国循环杂志

CSTPCD北大核心
影响因子:2.803
ISSN:1000-3614
年,卷(期):2024.39(12)