Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease,with a prevalence of about 29.2％ in China.A large number of clinical studies have shown that NAFLD is closely related to cardiovascular-related metabolic diseases such as obesity,dyslipidemia,diabetes mellitus,hypertension,etc.,and NAFLD is an independent risk factor for atherosclerotic cardiovascular disease (ASCVD),and cardiovascular disease is the leading cause of death in patients with NAFLD.This article reviews the relationship between NAFLD and metabolic dysfunction-associated fatty liver disease (MAFLD) with ASCVD and related metabolic diseases,and discusses the related pathophysiological mechanisms such as insulin resistance,oxidative stress,and inflammation,aiming to provide practical recommendations for reducing the risk of NAFLD-associated cardiovascular disease.
维普
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