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强迫症反应抑制缺陷(综述)

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强迫症是一种常见的高致残性精神障碍,伴随多种认知功能的缺陷。其中,反应抑制缺陷可能是强迫症的一种潜在的内表型,对于理解强迫症的病理生理机制和开发新的临床治疗方法具有重要意义。本文综述了强迫症反应抑制缺陷及其神经机制和临床干预效果,以期为进一步理解强迫症反应抑制缺陷和促进强迫症的临床诊疗提供依据。
A review of deficits in response inhibition of obsessive-compulsive disorder
Obsessive-compulsive disorder(OCD)is a prevalent and profoundly debilitating mental disorder characterized by various cognitive impairments.Among them,deficiency in response inhibition may be a potential endophenotype,playing a critical role in comprehending the underlying pathophysiological mechanisms of OCD and facilitating the development of novel clinical treatment approaches.This article reviews the response inhibition defi-cit in OCD,including its neural mechanisms and the effects of clinical interventions,in order to provide evidence for further understanding of the response inhibition deficit in OCD and promote the clinical diagnosis and treatment of OCD.

obsessive-compulsive disorderresponse inhibitionfrontal lobe-basal ganglia modelreview

张晨、范青

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上海交通大学医学院附属精神卫生中心,上海 200030

强迫症 反应抑制 额叶-基底神经节模型 综述

国家自然科学基金面上项目上海交通大学"交大之星"计划医工交叉研究基金重点项目

81771460YG2021ZD28

2024

中国心理卫生杂志
中国心理卫生协会

中国心理卫生杂志

CSTPCDCHSSCD北大核心
影响因子:2.088
ISSN:1000-6729
年,卷(期):2024.38(4)
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