摘要
目的:了解终末期癌症患者照顾者的自杀行为,并探讨睡眠相关症状、生活质量、抑郁症状与自杀行为的关系.方法:选取213例终末期癌症患者,采用世界卫生组织生存质量测定量表简表(WHOQOL-BREF)、病人健康问卷(PHQ-9)、睡眠相关症状3个标准化问题及自杀行为3个标准化问题对其照顾者进行调查.结果:自杀行为检出率为16.43％.终末期癌症患者照顾者生活质量得分与抑郁症状得分、睡眠相关症状、自杀行为呈负相关(r=-0.66、-0.29、-0.44,均P＜0.01),抑郁症状得分、睡眠相关症状、自杀行为两两之间均呈正相关(r=0.27、0.51、0.10,均P＜0.01).生活质量得分在抑郁症状得分和睡眠相关症状关系中的中介效应有统计学意义(r=0.29),中介效应占总效应的55％;抑郁症状得分在睡眠相关症状对自杀行为的影响中起完全中介效应(r=0.34,P＜0.05).结论:终末期癌症患者照顾者自杀行为检出率高,睡眠相关症状、生活质量、抑郁症状可能是自杀行为的相关因素.
Abstract
Objective:To understand suicide behavior in caregivers of patients with end-stage cancer and to explore the relationship between sleep-related symptoms,quality of life,depressive symptoms,and suicide behavior.Methods:Two hundred and thirteen caregivers of end-stage cancer patients were assessed with the World Health Organization Quality of Life(WHOQOL-BREF),Patient Health Questionnaire(PHQ-9),3 standardized questions for sleep-related symptoms,and 3 standardized questions for suicide behavior.Results:The detection rate of suicide behavior was 16.43％.Quality of life scores were negatively correlated with depressive symptom scores,sleep-related symptoms,and suicide behavior(r=-0.66,-0.29,-0.44,Ps＜0.01),and positive correlations were found between depressive symptom scores,sleep-related symptoms,and suicide behavior(r=0.27,0.51,0.10,Ps＜0.01).The mediating effect of quality of life scores in the relationship between depressive symptom scores and sleep-related symptoms was statistically significant(r=0.29),with the mediating effect accounting for 55％ of the total effect;depressive symptom scores played a full mediating effect in the effect of sleep-related symptoms on suicide behavior(r=0.34,P＜0.05).Conclusions:Among caregivers of patients with end-stage cancer,suicide behavior is detected at a high rate,and sleep-related symptoms,quality of life,and depressive symp-toms may be correlates of suicide behavior.
维普
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