Suicide behavior and related factors in caregivers of patients with end-stage cancer
Objective:To understand suicide behavior in caregivers of patients with end-stage cancer and to explore the relationship between sleep-related symptoms,quality of life,depressive symptoms,and suicide behavior.Methods:Two hundred and thirteen caregivers of end-stage cancer patients were assessed with the World Health Organization Quality of Life(WHOQOL-BREF),Patient Health Questionnaire(PHQ-9),3 standardized questions for sleep-related symptoms,and 3 standardized questions for suicide behavior.Results:The detection rate of suicide behavior was 16.43%.Quality of life scores were negatively correlated with depressive symptom scores,sleep-related symptoms,and suicide behavior(r=-0.66,-0.29,-0.44,Ps<0.01),and positive correlations were found between depressive symptom scores,sleep-related symptoms,and suicide behavior(r=0.27,0.51,0.10,Ps<0.01).The mediating effect of quality of life scores in the relationship between depressive symptom scores and sleep-related symptoms was statistically significant(r=0.29),with the mediating effect accounting for 55% of the total effect;depressive symptom scores played a full mediating effect in the effect of sleep-related symptoms on suicide behavior(r=0.34,P<0.05).Conclusions:Among caregivers of patients with end-stage cancer,suicide behavior is detected at a high rate,and sleep-related symptoms,quality of life,and depressive symp-toms may be correlates of suicide behavior.