Heat stress is one of the major environmental stress challenges facing chicken production worldwide,and is the sum of a number of non-specific stress responses that animals exhibit when exposed to the external environment.Heat stress can lead to reduced feed intake,reduced growth performance,altered blood biochemical parameters and disturbances in the gut microflora,which can seriously affect chicken productivity.Heat stress can also reduce the defense mechanisms and immune function of chickens,increase the expression of inflammatory factors,cause an increase in body antioxidant indicators,and significantly affect the composition and diversity of gut microbiota,with Escherichia coli and Bacillus methanogens as important predictors that play an important role in foresight.Physiological adjustments in chickens under heat stress conditions include increased heart rate,rapid respiration and increased oxidative metabolism in the body.In the actual production process,the harm caused by heat stress can be effectively alleviated by strengthening breeding management,improving the breeding environment,and adding anti-stress substances,such as trace element zinc and various vitamins.The authors synthesize the effects of heat stress on the production performance,serum biochemistry,antioxidants and the structure of gut microbiota in chicken,so as to provide a theoretical basis for preventing heat stress during chicken breeding.