Research Progress on the Regulation of Non-coding RNA in Muscle Fiber-type Conversion in Animals
Non-coding RNA(ncRNA)is an RNA molecule transcribed from the genome that does not code for proteins,including microRNA(miRNA),long non-coding RNA(lncRNA),circular RNA(circRNA)and RNA of unknown function.The function of ncRNA is to perform various regulatory functions in cells,such as participating in gene expression regulation,DNA repair,cell division and other biological processes.ncRNA can target and regulate gene transcription which in turn modulates muscle growth and development.Myofibers are the basic structural unit of muscle,and different muscle fiber-type of organisms act differently.Moreover,meat comprising different muscle fiber types varies in color,texture,nutrient content and water retention.Hence,it is significant to conduct research on muscle fiber-type conversion to achieve improved meat quality.Whereas,as a critical regulator in the transformation of myofiber types,ncRNA is a research hotspot that can not be ignored.In this paper,based on three kinds of ncRNA,which are miRNA,lncRNA and circRNA,the authors reviewed the concepts of ncRNA and muscle fiber-type and the current research status of ncRNA regulating the muscle fiber-type conversion,in order to provide important references for the application of ncRNA in improving the meat quality of livestock and poultry.
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