Research Progress on the Regulation of Animal Intestinal Microbiota by Mulberry Leaves and Its Active Substances
Mulberry leaves not only have high nutritional value,but also are rich in a variety of biologically active substances such as mulberry leaf flavonoids,mulberry leaf polysaccharides,alkaloids and γ-aminobutyric acid.These active substances have multiple functions for microorganisms.On the one hand,active substances in mulberry leaves can disrupt the structure and genetic material of bacteria by binding or competing with them for substrates required for growth,thereby inhibiting the proliferation of harmful bacteria.On the other hand,microorganisms in intestine can decompose and convert these active substances into small molecules with higher biological activity or lower toxicity with the assistance of enzymes,improving the relative abundance of beneficial bacteria in intestine,increasing the generation of short chain fatty acids such as acetic acid and butyric acid in intestine,promoting the synthesis of tight junction proteins,thereby promoting digestion and absorption in intestine,enhancing the body's antioxidant and immune abilities,and maintaining the intestinal barrier function of animals.Good intestinal status is an important guarantee for the healthy growth of animals.In the context of today's highly intensive breeding model and the ban on antibiotics in feed,mulberry leaves and its active substances have important functions such as maintaining animal intestinal health.They are ideal substitutes for antibiotics and can be used to develop green and efficient feed additives.The authors provide a comprehensive explanation of the main active substances in mulberry leaves,their interaction with microorganisms,and the impact of mulberry leaves and their active substances on the intestinal microorganisms of livestock,poultry,and aquatic animals.Furthermore,the authors also put forward his own opinions on the focus of future research on mulberry leaf resources.This paper aims to provide valuable reference material for the application of mulberry leaves in livestock,poultry and aquatic animal feed.
mulberry leavesactive substance of mulberry leavesintestinal microbiotaintestinal health
万方数据
维普
