首页|胍基乙酸对育肥猪生长性能、血清生化指标、抗氧化能力和免疫功能的影响

胍基乙酸对育肥猪生长性能、血清生化指标、抗氧化能力和免疫功能的影响

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  • 国家科技期刊平台
  • NETL
  • NSTL
  • 万方数据
[目的]研究饲粮中添加胍基乙酸对育肥猪生长性能、血清生化指标、抗氧化能力和免疫功能的影响，为胍基乙酸在生猪养殖业中的应用提供参考。[方法]选取36头体重相近且健康的杜×长×大三元杂交母猪，随机分为3组，每组6个重复，每个重复2头。对照组猪饲喂基础饲粮;试验组猪分别在基础饲粮中添加0。1％胍基乙酸(GAA组)和0。1％胍基乙酸+0。04％甜菜碱(GAA+BT组)，试验期50 d。试验结束时，以重复为单位称育肥猪空腹重，计算育肥猪的生长性能;每个重复挑选1头猪进行前腔静脉采血，测定血清生化指标、抗氧化能力和免疫功能。[结果]①饲粮中添加胍基乙酸对育肥猪的生长性能无显著影响(P＞0。05)。②与对照组相比，GAA和GAA+BT组育肥猪血清中总蛋白、球蛋白、白细胞介素-2、白细胞介素-10、γ-干扰素和免疫球蛋白A含量均显著升高，GAA组育肥猪血清中免疫球蛋白G含量显著升高(P＜0。05);GAA和GAA+BT组育肥猪血清中肌酐、尿酸和乳酸脱氢酶水平均显著降低，GAA+BT组育肥猪血清中丙二醛含量显著降低(P＜0。05)。③与对照组和GAA组相比，GAA+BT组育肥猪血清中总抗氧化能力显著升高(P＜0。05)。④与对照组和GAA+BT组相比，GAA组育肥猪血清中肿瘤坏死因子-α含量显著升高(P＜0。05)。[结论]饲粮中添加胍基乙酸不影响育肥猪的生长性能，但可改善育肥猪机体代谢水平，增强抗氧化能力和免疫功能，且单独使用和联合添加甜菜碱均具有效果。
Effects of Guanidinoacetic Acid on Growth Performance,Serum Biochemical Indices,Antioxidant Capacity and Immune Function of Finishing Pigs
[Objective]The aim of this study was to explore the effects of dietary supplementation with guanidinoacetic acid on the growth performance,serum biochemical indices,antioxidant capacity and immune function of finishing pigs,and provide reference for the application of guanidinoacetic acid in pig breeding industry.[Method]Thirty-six healthy Duroc × Landrace × Yorkshire three-way crossbred sows with similar body weights were randomly divided into 3 groups with 6 replicates per group and 2 sows per replicate.Finishing pigs in control group were fed basal diet,and finishing pigs in experiment group were supplemented with 0.1％guanidinoacetic acid(GAA group)and 0.1％guanidinoacetic acid+0.04％betaine(GAA+BT group)in basal diet,respectively.The experiment lasted for 50 d.At the end of the experiment,finishing pigs were weighed on empty stomachs in replicates and calculated for growth performance,one pig was selected from each replicate for vena cava blood sampling to determine serum biochemical indices,antioxidant capacity and immune function.[Result]① Dietary supplementation with guanidinoacetic acid had no significant effect on growth performance of finishing pigs(P＞0.05).② Compared with control group,the contents of total protein,globulin,interleukin-2,interleukin-10,interferon-γ and immunoglobulin A in serum of finishing pigs in GAA and GAA+BT groups were significantly increased,and the immunoglobulin G content in serum of finishing pigs in GAA group was significantly increased(P＜0.05).The levels of creatinine,uric acid and lactate dehydrogenase in serum of finishing pigs in GAA and GAA+BT groups were significantly decreased,and the malondialdehyde content in serum of finishing pigs in GAA+BT group was significantly decreased(P＜0.05).③ Compared with control and GAA groups,the total antioxidant capacity in serum of finishing pigs in GAA+BT group was significantly increased(P＜0.05).@Compared with control and GAA+BT groups,the tumor necrosis factor-α content in serum of finishing pigs in GAA group was significantly increased(P＜0.05).[Conclusion]Dietary supplementation with guanidinoacetic acid did not affect the growth performance of finishing pigs,however,it could improve the metabolism level,enhance the antioxidant capacity and immune function of finishing pigs,and it was effective both alone and in combination with the addition of betaine.

guanidinoacetic acidfinishing pigsgrowth performanceserum biochemical indicesantioxidant capacityimmune function

李贞明、马现永、容庭、崔艺燕、宋敏、刘志昌、邓盾、田志梅、余苗

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广东省农业科学院动物科学研究所,猪禽种业全国重点实验室,农业农村部华南动物营养与饲料重点实验室,广东省畜禽育种与营养研究重点实验室,广东省畜禽肉品质量安全控制与评定工程技术研究中心,广州 510640

清远市龙发种猪有限公司,清远 511500

岭南现代农业科学与技术广东省实验室茂名分中心,茂名 525032

岭南现代农业科学与技术广东省实验室河源分中心,河源 517000

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胍基乙酸 育肥猪 生长性能 血清生化指标 抗氧化能力 免疫功能

清远市创新创业科研团队项目广东省乡村振兴战略专项广东省乡村振兴战略专项猪禽种业全国重点实验室项目猪禽种业全国重点实验室项目科技创新战略专项(高水平农科院建设)科技创新战略专项(高水平农科院建设)岭南现代农业科学与技术广东省实验室河源分中心自主科研项目岭南现代农业科学与技术广东省实验室茂名分中心基金资助课题

20180022023KJ4652023TS-32023QZ-NK09ZQQZ-03R2023PY-JX015R2020YJ-YB2002DT202200222021TDQD002

2024

10.16431/j.cnki.1671-7236.2024.08.009

中国畜牧兽医
中国农业科学院北京畜牧兽医研究所

中国畜牧兽医

CSTPCD北大核心
影响因子：0.72
ISSN：1671-7236
年,卷(期)：2024.51(8)