Biological threats to global malaria elimination Ⅰ Antimalarial drug resistance
Malaria is an infectious disease that seriously threatens human health.Currently,malaria control mainly depends on antimalarial chemotherapy.However,antimalarial drug resistance is becoming increasingly severe,which poses a great challenge to malaria control,notably treatment of Plasmodium falciparum malaria.To address this challenge,there is a need to facilitate de-velopment of novel antimalarial drugs and innovation of treatment strategies,as well as reinforce surveillance and research on an-timalarial drug resistance.This article reviews the main categories and use guidelines of current antimalarial agents,summarizes the current status and monitoring methods of antimalarial drug resistance,and proposes the response to antimalarial drug resis-tance,so as to provide insights into the use of antimalarial drugs and response to antimalarial drug resistance,and contribute to global malaria elimination.
MalariaEliminationAntimalarial drug resistanceResistance management