Biological threats to global malaria elimi-nation Ⅲ Vector insecticide resistance
The insecticide resistance is becoming increasingly severe in malaria vectors and has become one of the most impor-tant threats to global malaria elimination.Currently,malaria vectors not only have developed high resistance to conventional in-secticides,including organochlorine,organophosphates,carbamates,and pyrethroids,but also have been resistant to recently used neonicotinoids and pyrrole insecticides.This article describes the current status of global insecticide resistance in malaria vectors and global insecticide resistance management strategies,analyzes the possible major challenges in the insecticide resis-tance management,and proposes the response actions,so as to provide insights into global insecticide resistance management and contributions to global malaria elimination.