摘要
蝎毒液是一种具有生物活性的复杂混合物,主要包含黏蛋白类、酶类、脂类、生物活性多肽及其他有机或无机分子.蝎毒抗菌肽是从蝎毒液中分离出来的小分子多肽,具有抗病毒、抗细菌、抗真菌和抗肿瘤细胞等生物活性.本文对蝎毒液及其抗菌肽抗寄生虫活性的国内外研究进展进行了综述,以期为新型抗寄生虫类药物的研发提供参考.
Abstract
Scorpion venom is a highly complicated cocktail of bioactive components including mucoproteins,enzymes,lipids,bioactive peptides,and other organic or inorganic molecules.Scorpion venom antimicrobial peptides are a class of small-mole-cule bioactive peptides extracted from scorpion venoms,which have shown a variety of biological activities,including antiviral,antibacterial,antifungal and antitumor actions.This review describes the progress of researches on the antiparasitic activities of scorpion venoms and their antimicrobial peptides,so as to provide insights into the research and development of novel antiparasit-ic agents.
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