Early and mid-term curative effect of modified repair of ventricular septal defect in children and establishment of prediction model for complicated arrhythmia
Early and mid-term curative effect of modified repair of ventricular septal defect in children and establishment of prediction model for complicated arrhythmia
Objective To explore the early and mid-term effects of the improved repair of ventricular septal defect in children and the factors of postoperative arrhythmia and to establish a risk prediction model.Methods The clinical data of 100 children with septal defect admitted to Xuzhou Children's Hospital and treated with the improved repair from October 2022 to October 2023 were collected.The perioperative indexes and cardiac function before and after the operation were observed.The parameters of postoperative arrhythmia and non-arrhythmia were analyzed.The receiver operating characteristic curve(ROC curve)was used to draw the prediction model of arrhythmia.Results At 1 month and 3 months after the operation,the left ventricular end diastolic diameter,pulmonary artery diameter and pulmonary valve blood flow velocity were significantly lower than those before the operation.The aortic orifice blood flow velocity was significantly higher than that before the operation(P＜0.05).Among the 100 children,15 cases(15.00％)developed postoperative arrhythmia.The clinical parameters of the two groups showed that the age,repair type,repair diameter,preoperative arrhythmia,operation time,preoperative pulmonary artery diameter and preoperative pulmonary valve blood flow velocity were the suspicious influencing factors(P＜0.05).Further logistic regression analysis showed that the age,surgical repair type,repair diameter,preoperative arrhythmia and operation time were the main factors leading to postoperative arrhythmia(P＜0.05).According to the joint data obtained by regression coefficient fitting,ROC analysis showed that the prediction AUC of the joint prediction model was 0.980 and the sensitivity and specificity of prediction were 93.3％and 98.8％respectively.Conclusion After the improved repair of ventricular septal defect in children,the cardiac function recovered better.The main factors of early and middle postoperative arrhythmia include the age,surgical repair type,repair diameter,preoperative arrhythmia and operation time,which should be pay more attention in clinic.
关键词
儿童室间隔缺损/改良修补术/早中期/疗效/心律失常/预测模型
Key words
Ventricular septal defect in children/Improved repair/Early and middle period/Therapeutic effect/Arrhythmia/Prediction mode
维普
万方数据