The relationship between preoperative blood calcium level and postoperative delirium in elderly patients undergoing cardiac surgery based on propensity score matching method
The relationship between preoperative blood calcium level and postoperative delirium in elderly patients undergoing cardiac surgery based on propensity score matching method
Objective To explore the relationship between preoperative blood calcium level and postoperative delirium in elderly patients undergoing cardiac surgery based on propensity score matching method(PSM).Methods The data of 166 elderly patients who received surgical treatment in the Department of Cardiac Surgery of the hospital from May 2020 to October 2023 were retrospectively analyzed;according to whether delirium occurred during the postoperative hospitalization,they were divided into the developing group(52 cases)and non-developing group(114 cases).PSM was used to match the clinical data of the two groups to obtain samples with balanced covariates between the 2 groups;univariate and logistic multivariate regression analysis were used to identify the risk factors for postoperative delirium,and receiver operating characteristic curve(ROC)was used to evaluate the efficacy of preoperative blood calcium level in predicting postoperative delirium.Results After PSM,a total of 47 pairs of covariate balanced samples were obtained.There were significant differences in the proportion of diabetes mellitus and red blood cells transfused after operation,and the levels of albumin,serum creatinine,serum calcium and neuro-specific enolase(NSE)between the developing group and the non-developing group(P＜0.05);there were no significant differences in the proportion of hypertension and hyperlipidemia,type of operation,hemoglobin and platelet count(P＞0.05).Logistic multivariate regression analysis showed that diabetes mellitus(OR=1.790,95％CI 1.627～1.952),low albumin level(OR=1.804,95％CI 1.516～2.092),high serum creatinine level(OR=1.844,95％CI 1.563～2.125),high blood calcium level(OR=1.835,95％CI 1.612～2.058),high NSE level(OR=1.840,95％CI 1.524～2.157),postoperative red blood cell transfusion(OR=1.808,95％CI 1.458～2.254)were the risk factors of postoperative delirium.ROC curve results showed that the sensitivity,specificity and AUC of preoperative blood calcium level in predicting postoperative delirium were 87.50％,77.30％and 0.906 respectively.Conclusion The risk of postoperative delirium in the elderly patients undergoing cardiac surgery is high,preoperative blood calcium level is closely related to postoperative delirium and the increase of preoperative blood calcium level may be an effective predictor of postoperative delirium in elderly patients undergoing cardiac surgery.
维普
万方数据