The Wnt pathway is a signaling pathway that plays a key role in the body.It regulates cell proliferation,development,differentiation,regeneration and embryonic development.It is essential for maintaining normal tissue function.It is also a signaling pathway that plays a key role in the development of diseases.In the past few decades,in-depth research on the Wnt pathway has enabled us to better understand its mechanism and has shown important influence in many fields.Myocardial fibrosis is an ischemic cardiomyopathy caused by myocardial ischemia and hypoxia which is a common pathological feature of various heart diseases.With in-depth research on the mechanism of myocardial fibrosis,it has been found that the Wnt pathway plays an important role in myocardial fibrosis.In recent years,a large number of experiments have also confirmed that many clinical drugs improvemyocardial fibrosis through the Wnt pathway.By summarizing the basic principles and regulatory mechanisms of the Wnt pathway and the effects of traditional Chinese and Western medicine on myocardial fibrosis through the Wnt pathway,an in-depth understanding of the Wnt pathway will help further understand many important issues and provide new insights into the treatment and prevention of diseases.
关键词
心肌纤维化/Wnt通路/西药/天然提取物/中药
Key words
Myocardial fibrosis/Wnt pathway/Western medicine/Natural extracts/Traditional Chinese medicine