中国心血管病研究2024,Vol.22Issue(7) :665-670.DOI:10.3969/j.issn.1672-5301.2024.07.014

冠状动脉钙化性病变的相关研究进展

Research progress of coronary artery calcification

聂铭 赵振舟 史青博 刘开源 李牧蔚
中国心血管病研究2024,Vol.22Issue(7) :665-670.DOI:10.3969/j.issn.1672-5301.2024.07.014

冠状动脉钙化性病变的相关研究进展

Research progress of coronary artery calcification

聂铭 1赵振舟 1史青博 1刘开源 1李牧蔚1
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作者信息

  • 1. 450000 河南省郑州市,河南大学人民医院河南省人民医院阜外华中医院冠心病二病区
  • 折叠

摘要

冠状动脉钙化(CAC)常被视为动脉粥样硬化的自然过程,作为一种血管退行性疾病,其主要原因在于钙盐在冠状动脉壁上异常沉积,进而波及血管中膜以及血管内膜,使得血管壁硬化,血管舒张反应减弱,从而对冠状动脉血流产生影响.相关研究揭示,CAC程度反映了冠状动脉疾病的严重程度,与未来心血管事件的风险呈正相关.本文根据近年来CAC相关研究进展,从病变发生机制、检测方法、治疗方案及其优劣性研究进展进行综述.

Abstract

Coronary artery calcification(CAC)is often regarded as a natural process of atherosclerosis.As a vascular degenerative disease,the main cause of coronary artery calcification is the abnormal deposition of calcium salts on the coronary artery wall,which then spreads to the tunica media and tunica intima of the blood vessels,resulting in the hardening of the vessel wall and the weakening of the vasodilation response,thus affecting the blood flow of the coronary artery.Studies have shown CAC is closely related to the severity of coronary atherosclerosis and the incidence of future cardiac events.This article reviews the research progress of CAC in recent years,including the pathogenesis,detection methods,treatment options and their advantages and disadvantages.

关键词

冠状动脉/钙化/进展

Key words

Coronary artery/Calcification/Progress

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基金项目

河南省自然科学基金(202300410465)

河南省医学科技公关联合共建项目(LHGJ20220108)

出版年

2024
中国心血管病研究
中国医师协会,煤炭总医院

中国心血管病研究

CSTPCD
影响因子:0.878
ISSN:1672-5301
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