Changes of axial length in primary and secondary school students in Yunnan and associated factors
Objective To explore the pattern of change of axial length/curvatrue radius ratio(AL/CR)and associated factors in primary and secondary school students in Yunnan,so as to provide scientific basis and prospective guidance for early myopia inter-vention and control.Methods A total of 685 students from grades 2 to 3 and grade 7 in 2 cities/counties in Yunnan Province were selected by multi-stage stratified random cluster sampling method in 2020.All the participants were followed up twice with question-naire of myopia related factors,uncorrected distance visual acuity,and refractive parameter measurement from October,2021 and March,2023,respectivelty.The distribution and change of AL/CR in different classes and groups were analyzed,and the influen-cing factos of AL/CR cumulative progression were explored using generalized linear model.Results AL/CR ratio in primary school students was(2.95±0.09)at baseline,increased to(2.99±0.11)at the first follow-up and(3.04±0.12)at the second follow-up.AL/CR ratio in middle school students(3.08±0.13)at baseline,increased to(3.12±0.15)at the first follow-up and(3.15±0.14)at the second follow-up.The generalized linear model showed that after controlling for environmental factors,ethnicity(β=-0.017),cumulative progression of the SE(β=-0.027)influenced the changes of AL/CR ratio among the primary school students,whereas the changes of AL/CR ratio were associated with baseline AL(β=-0.005),baseline corneal curvatrue radius(β=0.032)and cu-mulative progression of SE(β=-0.035)among middle school students(P＜0.05).Conclusions The AL/CR ratio of primary and secondary school students in Yunnan can be used to judge different refractive status types,but its variation is not only related to SE progression,but also affected by different ethnic groups and baseline ocular biological parameters.so the value of AL/CR applica-tion in assessing the progression of myopia needs to be further confirmed.
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