云南地区中小学生眼轴变化及影响因素分析
Changes of axial length in primary and secondary school students in Yunnan and associated factors
肖洁 1苏梅慧 2李佩谦 1黄达峰 3李茜茜 1马子雪 1罗筱 1陈茂森 1黄莹1
作者信息
- 1. 昆明医科大学公共卫生学院,云南 650500
- 2. 西双版纳傣族自治州勐海县疾病预防控制中心
- 3. 云南省疾病预防控制中心学校卫生所
- 折叠
摘要
目的 探讨云南地区中小学生眼轴长度与角膜曲率半径比值(AL/CR)变化规律及其影响因素,为早期近视干预控制提供科学依据.方法 采用多阶段分层整群随机抽样方法,于2020年抽取云南省2个市/县二、三年级和七年级共685名学生分别于2021年10月、2023年3月进行随访,调查内容包括近视相关因素问卷调查、裸眼远视力、屈光参数测量,分析AL/CR在不同学段不同组别间的分布及变化,采用广义线性模型探索AL/CR累积进展量的影响因素.结果 小学生基线AL/CR值为(2.95±0.09),第1次随访增加至(2.99±0.11),第2次随访增加至(3.04±0.12).中学生基线AL/CR值为(3.08±0.13),第1次随访增加至(3.12±0.15),第2次随访增加至(3.15±0.14).广义线性模型结果显示控制环境因素后,小学生中白族(β=-0.017)、等效球境度数(SE)累积进展量(β=-0.027)影响AL/CR变化;中学生AL/CR变化与基线AL(β=-0.005)、基线CR(β=0.032)及SE累积进展量(β=-0.035)相关(P值均＜0.05).结论 云南地区中小学生AL/CR可用于判断不同屈光状态类型,其变化量除与SE进展有关,还受民族、基线眼生物学参数的影响.AL/CR应用于评估近视进展方面的价值需进一步证实.
Abstract
Objective To explore the pattern of change of axial length/curvatrue radius ratio(AL/CR)and associated factors in primary and secondary school students in Yunnan,so as to provide scientific basis and prospective guidance for early myopia inter-vention and control.Methods A total of 685 students from grades 2 to 3 and grade 7 in 2 cities/counties in Yunnan Province were selected by multi-stage stratified random cluster sampling method in 2020.All the participants were followed up twice with question-naire of myopia related factors,uncorrected distance visual acuity,and refractive parameter measurement from October,2021 and March,2023,respectivelty.The distribution and change of AL/CR in different classes and groups were analyzed,and the influen-cing factos of AL/CR cumulative progression were explored using generalized linear model.Results AL/CR ratio in primary school students was(2.95±0.09)at baseline,increased to(2.99±0.11)at the first follow-up and(3.04±0.12)at the second follow-up.AL/CR ratio in middle school students(3.08±0.13)at baseline,increased to(3.12±0.15)at the first follow-up and(3.15±0.14)at the second follow-up.The generalized linear model showed that after controlling for environmental factors,ethnicity(β=-0.017),cumulative progression of the SE(β=-0.027)influenced the changes of AL/CR ratio among the primary school students,whereas the changes of AL/CR ratio were associated with baseline AL(β=-0.005),baseline corneal curvatrue radius(β=0.032)and cu-mulative progression of SE(β=-0.035)among middle school students(P＜0.05).Conclusions The AL/CR ratio of primary and secondary school students in Yunnan can be used to judge different refractive status types,but its variation is not only related to SE progression,but also affected by different ethnic groups and baseline ocular biological parameters.so the value of AL/CR applica-tion in assessing the progression of myopia needs to be further confirmed.
关键词
眼轴长度/角膜曲率半径/因素分析,统计学/学生Key words
Ocular axial length/Corneal curvature radius/Factor analysis,statistical/Students引用本文复制引用
出版年
2024
NETL
NSTL
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