Relationship between metal exposure and blood pressure in rural primary school students in Shiyan City,Hubei Province
Objective To explore the relationship between metal exposure level and blood pressure,so as to provide a scientific basis for verifying the relationship between metal exposure and elevated blood pressure among primary school students.Methods In July 2022,a total of 555 students of second to sixth grade were selected by cluster random sampling method from two primary schools in Zhuxi County,Shiyan City,Hubei Province.A questionnaire survey was conducted to obtain the socio-demographic char-acteristics and living habits of the participants.The height,weight,body mass index(BMI)and blood pressure were obtained by physical examination.At the same time,the urine of the subjects was collected,and the metal mass fraction in urine was detected by inductively coupled plasma mass spectrometry.The relationship between metal mass fraction in urine and blood pressure was ana-lyzed by generalized linear regression.Results The detection rate of elevated blood pressure in primary school students was 15.86％,and there was a statistically significant difference in the detection rate of elevated blood pressure among obese primary school students(yes:37.25％,no:13.69％,x2=19.28,P＜0.01).There were statistically significant differences in BMI[15.80(14.69,17.92),17.87(15.49,20.89)kg/m2]between the non elevated blood pressure group and the elevated blood pressure group of elementary school students(Z=-4.67,P＜0.01).The geometric mean mass fraction of zinc in urine was the highest(6 942.86μg/g),titanium was the lowest(2.20 μg/g).Zinc and lead were positively correlated with elevated systolic blood pressure(β=0.054,0.014),zinc and cadmium were positively correlated with elevated diastolic blood pressure(P=0.038,0.029)(P＜0.05).Conclusions Metal zinc,lead and cadmium concentration are associated with elevated blood pressure.It is necessary to intervene and control the exposure of zinc,lead and cadmium in the environment to promote the blood pressure health of primary school students.
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