Objective To investigate the relationship between adverse childhood experiences(ACEs)and mental health status through network analysis in college students,so as to provide empirical evidence for the development of targeted intervention pro-grams.Methods From October to November 2023,a survey was conducted on 1 974 college students from three universities in Hubei Province by using ACEs Questionnaire and Symptom Checklist-90(SCL-90).The network analysis method was used to con-struct a network structure to analyze the association between ACEs and SCL-90 symptom factors among college students.Results The network structure of SCL-90 symptom factors and ACEs was stable,each forming a relatively tight cluster;there were 89 non-zero edges between ACEs and SCL-90 symptom factors.Emotional neglect-depression played a significant pathway role in connect-ing the ACEs and SCL-90 symptom factors network.Depression,anxiety,and interpersonal sensitivity of SCL-90 symptom factors had the highest centrality in the ACEs and SCL-90 symptom factors network.Emotional neglect and physical neglect in ACEs and depression and psychoticism in SCL-90 symptom factors had a high node bridge expected influence,acting as Touchpoints to acti-vate the whole network.Conclusion Early identification and intervention of emotional and physical neglect,with a focus on de-pression,anxiety,and interpersonal sensitivity symptoms of childhood neglected individuals,which is beneficial for improving the overall mental health level of college students.